$128 Cheap flight deals from Buffalo (BUF) to Key West (EYW)

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This Weekend's Flight Deals from Buffalo to Key West

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Apr 26 - Fri, May 9
BUF
Buffalo Niagara Intl.
EYW
Key West Intl.
$385 Roundtrip, found 2 days ago
$385
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Apr 26 from Buffalo Niagara Intl. to Key West Intl., returning Fri, May 9, priced at $385 found 2 days ago

Airfares from $128 One Way, $237 Round Trip from Buffalo to Key West

Prices starting at $237 for return flights and $128 for one-way flights to Key West were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, May 28 - Tue, Jun 3
BUF
Buffalo
EYW
Key West
$237 Roundtrip, found 1 day ago
$237
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, May 28 from Buffalo to Key West, returning Tue, Jun 3, priced at $237 found 1 day ago
Sun, Aug 31 - Tue, Sep 16
BUF
Buffalo
EYW
Key West
$244 Roundtrip, found 2 days ago
$244
Roundtrip
found 2 days ago
Select Delta flight, departing Sun, Aug 31 from Buffalo to Key West, returning Tue, Sep 16, priced at $244 found 2 days ago
Tue, Jul 1 - Tue, Jul 22
BUF
Buffalo
EYW
Key West
$245 Roundtrip, found 2 days ago
$245
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Jul 1 from Buffalo to Key West, returning Tue, Jul 22, priced at $245 found 2 days ago
Wed, May 28 - Thu, Jun 5
BUF
Buffalo
EYW
Key West
$246 Roundtrip, found 1 day ago
$246
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, May 28 from Buffalo to Key West, returning Thu, Jun 5, priced at $246 found 1 day ago
Sat, May 31 - Tue, Jun 17
BUF
Buffalo
EYW
Key West
$247 Roundtrip, found 2 days ago
$247
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, May 31 from Buffalo to Key West, returning Tue, Jun 17, priced at $247 found 2 days ago

Key West economy flight packages

Price found within the past 48 hours. Click for updated prices.
The Perry Hotel & Marina Key West
4.0-star property

The Perry Hotel & Marina Key West

9.4/10 Exceptional! (1,010 reviews)

Jun 2 - Jun 7

5 night stay

Buffalo (BUF) to Key West (EYW)

Delta • Non-stop roundtrip • Coach
per person
found 1 day ago
Excellent facility. The on site personnel were fabulous and the shuttle service is more than adequate.

Reviewed on Jan 5, 2025

Southernmost Beach Resort
4.0-star property

Southernmost Beach Resort

8.6/10 Excellent! (2,353 reviews)

Jun 2 - Jun 7

5 night stay

Buffalo (BUF) to Key West (EYW)

Delta • Non-stop roundtrip • Coach
Save 100% on your flight
per person
found 1 day ago
I really enjoyed my long weekend at the Southernmost Beach Resort. There are several pools, beaches, bars and a restaurant. My room was clean and spacious. All the staff I encountered were super friendly. Great location and easy walking distance to Duval.

Reviewed on Apr 1, 2025

Pier House Resort & Spa
4.0-star property

Pier House Resort & Spa

9/10 Wonderful! (1,006 reviews)

Jun 2 - Jun 7

5 night stay

Buffalo (BUF) to Key West (EYW)

Delta • Non-stop roundtrip • Coach
Save 100% on your flight
per person
found 1 day ago
Enjoyed this property for our Honeymoon. Stayed in a Traditional King Room, however, was wanting a better view then just the courtyard. The staff was excellent!!! Linda out by the bar and beach - she rocks !!! Best server around!!! Will return in the future.

Reviewed on Feb 20, 2025

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More About Flying To Key West from Buffalo

Route Information for Flights from Buffalo to Key West

Origin Airport IATA Code
BUF
Destination Airport IATA Code
EYW
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Buffalo to Key West

Those who want guaranteed low prices for Buffalo to Key West flights only need to visit Orbitz. We take advantage of the latest mobile technologies to make sure you get the best bargain on your trip and that everything goes smoothly and according to your plans.

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We will help you from booking to boarding on flights from Buffalo to Key West. Whether you have questions about baggage limits, seat assignments or anything else, we will be there to answer them for you.

Get Great Recommendations For Travel Ideas On Orbitz.com

We do not only get the best bargains on flights from Buffalo to Key West, but we can tell you what to do once you get there. Whether it is a music festival, hotel recommendation or list of local attractions, Orbitz can help make your travel plan more exciting.

Combine Car Rental With Your Discount Flight For Even More Savings

Not only can we get bargain deals on flights from Buffalo to Key West but we can book your transport as well. By combining car rental with Buffalo to Key West flights, you can be sure to save money and start moving as soon as you hit the ground.

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Frequently asked questions

Am I able to catch a flight from Buffalo to Key West now?
The Covid-19 Travel Advisor can help you with queries about travel restrictions and quarantine when taking a plane flight from Buffalo to Key West.
What is the shortest flight from Buffalo to Key West?
From Buffalo, the wonderful sights and sounds of Key West are at least 3 hours and 49 minutes away. Lock in your favorite seat, or maybe even upgrade to one with extra legroom, and fly to your destination in comfort.
If I am not able to travel due to COVID-19, can I cancel my flight to Key West?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Key West have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Key West with flexible change policies?
In most cases you’ll have the option to reschedule your flight to Key West without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2020 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data the cheapest month to fly is August. Perfect for those who need a weekend getaway, or just a break from it all before the weather changes. Be aware that the most expensive time to fly is the height of summer, with ticket prices peaking in the month of June.
How can I save money on flights?
To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you’ll generally get a much better deal. Those who tried this on Orbitz in 2020 saved up to 45% on their airfares. Get mixing and matching today!

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.