$129 Cheap flight deals from San Francisco (SJC) to Key West (EYW)

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This Weekend's Flight Deals from San Francisco to Key West

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Apr 26 - Tue, Apr 29
SJC
Norman Y. Mineta San Jose Intl.
EYW
Key West Intl.
$478 Roundtrip, found 1 day ago
$478
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Apr 26 from Norman Y. Mineta San Jose Intl. to Key West Intl., returning Tue, Apr 29, priced at $478 found 1 day ago
Sat, Apr 26 - Sat, May 3
SFO
San Francisco Intl.
EYW
Key West Intl.
$1,372 Roundtrip, found 3 days ago
$1,372
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Sat, Apr 26 from San Francisco Intl. to Key West Intl., returning Sat, May 3, priced at $1,372 found 3 days ago

Airfares from $129 One Way, $257 Round Trip from San Francisco to Key West

Prices starting at $257 for return flights and $129 for one-way flights to Key West were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 9 - Tue, Aug 12
SJC
San Jose
EYW
Key West
$257 Roundtrip, found 9 hours ago
$257
Roundtrip
found 9 hours ago
Select Delta flight, departing Sat, Aug 9 from San Jose to Key West, returning Tue, Aug 12, priced at $257 found 9 hours ago
Sun, Aug 10 - Tue, Aug 12
SFO
San Francisco
EYW
Key West
$257 Roundtrip, found 9 hours ago
$257
Roundtrip
found 9 hours ago
Select Delta flight, departing Sun, Aug 10 from San Francisco to Key West, returning Tue, Aug 12, priced at $257 found 9 hours ago
Mon, Oct 20 - Tue, Nov 4
SFO
San Francisco
EYW
Key West
$259 Roundtrip, found 5 days ago
$259
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Mon, Oct 20 from San Francisco to Key West, returning Tue, Nov 4, priced at $259 found 5 days ago
Sat, Jul 26 - Tue, Jul 29
SJC
San Jose
EYW
Key West
$262 Roundtrip, found 5 days ago
$262
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Jul 26 from San Jose to Key West, returning Tue, Jul 29, priced at $262 found 5 days ago
Tue, Oct 21 - Fri, Nov 7
SFO
San Francisco
EYW
Key West
$283 Roundtrip, found 5 days ago
$283
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Oct 21 from San Francisco to Key West, returning Fri, Nov 7, priced at $283 found 5 days ago

Key West economy flight packages

Price found within the past 48 hours. Click for updated prices.
Southernmost Beach Resort
4.0-star property

Southernmost Beach Resort

8.6/10 Excellent! (2,353 reviews)

Jun 9 - Jun 15

6 night stay

San Francisco (SFO) to Key West (EYW)

Frontier Airlines • Non-stop • Coach

Key West (EYW) to San Francisco (SFO)

United • Non-stop • Coach
Save 100% on your flight
per person
found 1 day ago
I really enjoyed my long weekend at the Southernmost Beach Resort. There are several pools, beaches, bars and a restaurant. My room was clean and spacious. All the staff I encountered were super friendly. Great location and easy walking distance to Duval.

Reviewed on Apr 1, 2025

The Grand Guesthouse
2.5-star property

The Grand Guesthouse

9.6/10 Exceptional! (1,001 reviews)

Jun 15 - Jun 21

6 night stay

San Francisco (SFO) to Key West (EYW)

Delta • Non-stop • Coach

Key West (EYW) to San Francisco (SFO)

American Airlines • Non-stop • Coach
Save 100% on your flight
per person
found 10 hours ago
Fantastic host in historic district. Loved the location. Took great care of us!!!

Reviewed on Feb 28, 2025

Hyatt Vacation Club at Windward Pointe, Key West
3.5-star property

Hyatt Vacation Club at Windward Pointe, Key West

9.4/10 Exceptional! (1,005 reviews)

May 29 - Jun 3

5 night stay

San Francisco (SFO) to Key West (EYW)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
per person
found 16 hours ago
Wonderful pool area!! Very spacious! Beautiful views! Very clean and spacious rooms! Right next to the airport. 10 min car ride to downtown.

Reviewed on Apr 15, 2025

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More About Flying To Key West from San Francisco

Route Information for Flights from San Francisco to Key West

Origin Airport IATA Code
SJC
Destination Airport IATA Code
EYW
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

San Francisco to Key West

Whether you want to book cheap flights from San Francisco to Key West or are looking for the perfect package holiday, Orbitz is your one-stop source. Taking the stress and expense out of travel, Orbitz helps you find the best fares for San Francisco to Key West flights.

Make the Most of Your Vacation

Not only does Orbitz have cheap deals for San Francisco to Key West flights, we can also help you plan your vacation in advance. Why wait in lengthy lines for tickets to shows, amusement parks, and other attractions when you could be making the most of your holiday? Add activities to your flight booking for fewer hassles once you arrive in Key West.

Planning on the Go

Book your flights from San Francisco to Key West wherever you are with the Orbitz app for Android and iPhone. Or simply use m.orbitz.com on your mobile browser to search and book the San Francisco to Key West flights that you want. And if you’re running late, you check your flight status and baggage claim information on your mobile device too too.

Craft Your Perfect Vacation

Orbitz takes the stress out of vacation planning with great deals on flights from San Francisco to Key West, hotels, car rentals, cruises, and more. Mix and match results for your perfect trip, or book a complete vacation package.

Keep Informed With Orbitz

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Frequently asked questions

Am I able to catch a flight from San Francisco to Key West now?
If you’re wondering about travel restrictions and quarantine requirements when traveling by plane from San Francisco to Key West, check out the Covid-19 Travel Advisor.
What is the shortest flight from San Francisco to Key West?
The fastest flight time from San Francisco Airport to Key West Intl. Airport is 6 hours and 11 minutes, which gives you more than enough time to indulge in a tipple or get swept up in a good movie.
If I am not able to travel due to COVID-19, can I cancel my flight to Key West?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Key West have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Key West with flexible change policies?
In most cases you’ll have the option to reschedule your flight to Key West without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2020 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data the cheapest month to fly is August. Perfect for those who need a weekend getaway, or just a break from it all before the weather changes. Be aware that the most expensive time to fly is the height of summer, with ticket prices peaking in the month of June.
How can I save money on flights?
To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you’ll generally get a much better deal. Those who tried this on Orbitz in 2020 saved up to 45% on their airfares. Get mixing and matching today!

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.