$126 Cheap flight deals from Myrtle Beach (MYR) to Key West (EYW)

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Airfares from $126 One Way, $224 Round Trip from Myrtle Beach to Key West

Prices starting at $224 for return flights and $126 for one-way flights to Key West were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Aug 27 - Sun, Aug 31
MYR
Myrtle Beach
EYW
Key West
$224 Roundtrip, found 12 hours ago
$224
Roundtrip
found 12 hours ago
Select Delta flight, departing Wed, Aug 27 from Myrtle Beach to Key West, returning Sun, Aug 31, priced at $224 found 12 hours ago
Wed, Aug 27 - Sun, Aug 31
MYR
Myrtle Beach
EYW
Key West
$233 Roundtrip, found 12 hours ago
$233
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Wed, Aug 27 from Myrtle Beach to Key West, returning Sun, Aug 31, priced at $233 found 12 hours ago
Wed, Jun 4 - Wed, Jun 11
MYR
Myrtle Beach
EYW
Key West
$249 Roundtrip, found 23 hours ago
$249
Roundtrip
found 23 hours ago
Select Delta flight, departing Wed, Jun 4 from Myrtle Beach to Key West, returning Wed, Jun 11, priced at $249 found 23 hours ago
Fri, Jun 6 - Wed, Jun 11
MYR
Myrtle Beach
EYW
Key West
$253 Roundtrip, found 23 hours ago
$253
Roundtrip
found 23 hours ago
Select Delta flight, departing Fri, Jun 6 from Myrtle Beach to Key West, returning Wed, Jun 11, priced at $253 found 23 hours ago
Tue, Jun 10 - Wed, Jun 11
MYR
Myrtle Beach
EYW
Key West
$255 Roundtrip, found 23 hours ago
$255
Roundtrip
found 23 hours ago
Select Delta flight, departing Tue, Jun 10 from Myrtle Beach to Key West, returning Wed, Jun 11, priced at $255 found 23 hours ago

Key West economy flight packages

Price found within the past 48 hours. Click for updated prices.
Lighthouse Hotel - Key West Historic Inns
3.5-star property

Lighthouse Hotel - Key West Historic Inns

9/10 Wonderful! (706 reviews)

Jun 8 - Jun 13

5 night stay

Myrtle Beach (MYR) to Key West (EYW)

American Airlines • Non-stop roundtrip • Coach
per person
found 1 day ago
This place is a much better place to stay than places closer to the cruise ship pier or off or whitehead or duval

Reviewed on Sep 22, 2024

Hyatt Vacation Club at Windward Pointe, Key West
3.5-star property

Hyatt Vacation Club at Windward Pointe, Key West

9.4/10 Exceptional! (1,005 reviews)

Jun 14 - Jun 20

6 night stay

Myrtle Beach (MYR) to Key West (EYW)

Delta • Non-stop • Coach

Key West (EYW) to Myrtle Beach (MYR)

American Airlines • Non-stop • Coach
per person
found 4 hours ago
Wonderful pool area!! Very spacious! Beautiful views! Very clean and spacious rooms! Right next to the airport. 10 min car ride to downtown.

Reviewed on Apr 15, 2025

Almond Tree Inn Hotel - Adults Only
3.5-star property

Almond Tree Inn Hotel - Adults Only

10/10 Exceptional! (1,004 reviews)

Jun 8 - Jun 13

5 night stay

Myrtle Beach (MYR) to Key West (EYW)

American Airlines • Non-stop roundtrip • Coach
per person
found 1 day ago
This is a super cute boutique type hotel. very clean, very comfy bed and room, Quite and staff was very friendly. they offer a really nice happy hour with food and breakfast. Parking on site.

Reviewed on Feb 18, 2025

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More About Flying To Key West from Myrtle Beach

Route Information for Flights from Myrtle Beach to Key West

Origin Airport IATA Code
MYR
Destination Airport IATA Code
EYW
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Myrtle Beach to Key West

Orbitz assures that you will receive cheap air fares on flights from Myrtle Beach to Key West and special deals that give you guaranteed low prices on hotels, cruises, car rentals, and anything else you need on your trip.

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Frequently asked questions

Am I able to catch a flight from Myrtle Beach to Key West now?
If you’re agonizing over travel restrictions and quarantine requirements when catching a flight from Myrtle Beach to Key West, go right to our Covid-19 Travel Advisor.
What is the shortest flight from Myrtle Beach to Key West?
Getting from MYR to Key West, FL Airport (EYW-Key West Intl.) takes at least 3 hours and 2 minutes. Enjoy a beverage and watch a show or two — it’s the ideal opportunity to just relax.
If I am not able to travel due to COVID-19, can I cancel my flight to Key West?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Key West have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Key West with flexible change policies?
In most cases you’ll have the option to reschedule your flight to Key West without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2020 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data the cheapest month to fly is August. Perfect for those who need a weekend getaway, or just a break from it all before the weather changes. Be aware that the most expensive time to fly is the height of summer, with ticket prices peaking in the month of June.
How can I save money on flights?
To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you’ll generally get a much better deal. Those who tried this on Orbitz in 2020 saved up to 45% on their airfares. Get mixing and matching today!

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.