$104 Cheap flight deals from St. Louis (STL) to Key West (EYW)

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This Weekend's Flight Deals from St. Louis to Key West

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Nov 29 - Thu, Dec 12
STL
Lambert-St. Louis Intl.
EYW
Key West Intl.
$313 Roundtrip, found 4 days ago
$313
Roundtrip
found 4 days ago
Select Delta flight, departing Fri, Nov 29 from Lambert-St. Louis Intl. to Key West Intl., returning Thu, Dec 12, priced at $313 found 4 days ago

Airfares from $104 One Way, $208 Round Trip from St. Louis to Key West

Prices starting at $208 for return flights and $104 for one-way flights to Key West were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Jan 29 - Wed, Feb 5
STL
St. Louis
EYW
Key West
$208 Roundtrip, found 7 hours ago
$208
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Jan 29 from St. Louis to Key West, returning Wed, Feb 5, priced at $208 found 7 hours ago
Wed, Jan 29 - Wed, Feb 5
STL
St. Louis
EYW
Key West
$213 Roundtrip, found 7 hours ago
$213
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Jan 29 from St. Louis to Key West, returning Wed, Feb 5, priced at $213 found 7 hours ago
Wed, Jan 29 - Wed, Feb 5
STL
St. Louis
EYW
Key West
$216 Roundtrip, found 7 hours ago
$216
Roundtrip
found 7 hours ago
Select Delta flight, departing Wed, Jan 29 from St. Louis to Key West, returning Wed, Feb 5, priced at $216 found 7 hours ago
Wed, Jan 29 - Wed, Feb 5
STL
St. Louis
EYW
Key West
$216 Roundtrip, found 7 hours ago
$216
Roundtrip
found 7 hours ago
Select Delta flight, departing Wed, Jan 29 from St. Louis to Key West, returning Wed, Feb 5, priced at $216 found 7 hours ago
Wed, Jan 29 - Wed, Feb 5
STL
St. Louis
EYW
Key West
$219 Roundtrip, found 7 hours ago
$219
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Jan 29 from St. Louis to Key West, returning Wed, Feb 5, priced at $219 found 7 hours ago

Key West economy flight packages

Price found within the past 48 hours. Click for updated prices.
Oceans Edge Key West Resort, Hotel & Marina
4.0-star property

Oceans Edge Key West Resort, Hotel & Marina

8.8/10 Excellent! (1,508 reviews)

Jan 2 - Jan 5

3 night stay

St. Louis (STL) to Key West (EYW)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
per person
found 1 day ago
This is our third visit to key west and staying at oceans edge. We must like it or wouldn’t keep going back. Already planning to go back in November. We live the pools and the restaurant and the marina with all of the fishing boats.

Reviewed on Sep 2, 2024

Coral Garden by Avantstay Great Location w/ Balcony & Shared Pool
4.0-star property

Coral Garden by Avantstay Great Location w/ Balcony & Shared Pool

6/10 (2 reviews)

Dec 26 - Jan 3

8 night stay

St. Louis (STL) to Key West (EYW)

United • Non-stop roundtrip • Coach
Save 100% on your flight
per person
found 1 day ago
Hyatt Vacation Club at Windward Pointe, Key West
3.5-star property

Hyatt Vacation Club at Windward Pointe, Key West

9.4/10 Exceptional! (999 reviews)

Jan 9 - Jan 16

7 night stay

St. Louis (STL) to Key West (EYW)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
per person
found 1 day ago
We just checked out and are already talking about how we can’t wait to come back! This property is beautiful, within walking distance of the airport, on the quiet side of things but an easy 15-30 minute Uber or drive to the hustle and bustle. Somehow the plane noise isn’t a problem from inside, even with ongoing air traffic. The staff is friendly, kind and respectful. The pool and grounds are well maintained. The views are beautiful. There is a Publix and a few restaurants nearby. You can fish across the street. We had a lovely time with our family (grandparents and toddler). You will too.

Reviewed on Nov 3, 2024

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More About Flying To Key West from St. Louis

Route Information for Flights from St. Louis to Key West

Origin Airport IATA Code
STL
Destination Airport IATA Code
EYW
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

St. Louis to Key West

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Frequently asked questions

Am I able to catch a flight from St. Louis to Key West now?
Our Covid-19 Travel Advisor can answer all your questions about current quarantine requirements and travel restrictions when taking a flight from St. Louis to Key West.
What is the shortest flight from St. Louis to Key West?
From St. Louis, the distinctive sights and sounds of Key West are at least 3 hours and 16 minutes away. Book your favorite seat, or perhaps even upgrade to one with extra legroom, and get to your destination in comfort.
If I am not able to travel due to COVID-19, can I cancel my flight to Key West?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Key West have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Key West with flexible change policies?
In most cases you’ll have the option to reschedule your flight to Key West without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2020 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data the cheapest month to fly is August. Perfect for those who need a weekend getaway, or just a break from it all before the weather changes. Be aware that the most expensive time to fly is the height of summer, with ticket prices peaking in the month of June.
How can I save money on flights?
To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you’ll generally get a much better deal. Those who tried this on Orbitz in 2020 saved up to 45% on their airfares. Get mixing and matching today!

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.