$100 Cheap flight deals from St. Louis (STL) to Key West (EYW)

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This Weekend's Flight Deals from St. Louis to Key West

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Mar 1 - Wed, Mar 5
STL
Lambert-St. Louis Intl.
EYW
Key West Intl.
$385 Roundtrip, found 4 days ago
$385
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Mar 1 from Lambert-St. Louis Intl. to Key West Intl., returning Wed, Mar 5, priced at $385 found 4 days ago

Airfares from $100 One Way, $217 Round Trip from St. Louis to Key West

Prices starting at $217 for return flights and $100 for one-way flights to Key West were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Apr 15 - Wed, Apr 23
STL
St. Louis
EYW
Key West
$217 Roundtrip, found 1 day ago
$217
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Apr 15 from St. Louis to Key West, returning Wed, Apr 23, priced at $217 found 1 day ago
Tue, May 6 - Wed, May 21
STL
St. Louis
EYW
Key West
$218 Roundtrip, found 2 days ago
$218
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, May 6 from St. Louis to Key West, returning Wed, May 21, priced at $218 found 2 days ago
Tue, Apr 15 - Thu, Apr 24
STL
St. Louis
EYW
Key West
$238 Roundtrip, found 1 day ago
$238
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Apr 15 from St. Louis to Key West, returning Thu, Apr 24, priced at $238 found 1 day ago
Tue, May 13 - Wed, May 28
STL
St. Louis
EYW
Key West
$239 Roundtrip, found 2 days ago
$239
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, May 13 from St. Louis to Key West, returning Wed, May 28, priced at $239 found 2 days ago
Tue, Mar 25 - Wed, Mar 26
STL
St. Louis
EYW
Key West
$248 Roundtrip, found 6 days ago
$248
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Mar 25 from St. Louis to Key West, returning Wed, Mar 26, priced at $248 found 6 days ago

Key West economy flight packages

Price found within the past 48 hours. Click for updated prices.
Southwinds Motel
2.0-star property

Southwinds Motel

8.8/10 Excellent! (1,057 reviews)

Mar 27 - Mar 30

3 night stay

St. Louis (STL) to Key West (EYW)

American Airlines • Coach

Key West (EYW) to St. Louis (STL)

Delta • Coach
per person
found 14 hours ago
Nice motel and close to Duvall St

Reviewed on Dec 13, 2024

Courtyard by Marriott Key West Waterfront
3.0-star property

Courtyard by Marriott Key West Waterfront

8.8/10 Excellent! (1,003 reviews)

Mar 27 - Mar 30

3 night stay

St. Louis (STL) to Key West (EYW)

American Airlines • Coach

Key West (EYW) to St. Louis (STL)

Delta • Coach
per person
found 14 hours ago
Love the small balcony, with a table and 2 chairs. It was perfect to unwind.

Reviewed on Jan 30, 2024

Duval Corner Updated Condo Steps to Duval St
2.0-star property

Duval Corner Updated Condo Steps to Duval St

No reviews

Mar 27 - Mar 30

3 night stay

St. Louis (STL) to Key West (EYW)

American Airlines • Coach

Key West (EYW) to St. Louis (STL)

Delta • Coach
per person
found 14 hours ago
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More About Flying To Key West from St. Louis

Route Information for Flights from St. Louis to Key West

Origin Airport IATA Code
STL
Destination Airport IATA Code
EYW
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

St. Louis to Key West

Find fantastic fares on domestic and international flights that suit your travel requirements and budget needs by heading to Orbitz. Orbitz has your cheap air tickets for flights from St. Louis to Key West.

Flights from St. Louis to Key West at bargain prices

Budgeting and hidden costs should be the least of your concerns when planning a trip. Your priority should be planning all the things you want to do during your stay. With our low fares on St. Louis to Key West flights, you know you are getting the best deal for your vacation or business trip budget—and not incurring hidden costs or paying for over-priced tickets offered by some airlines. We want to help you enjoy your trip the way you deserve.

Remain up-to-date on your flights from St. Louis to Key West

Orbitz ensures that you remain up-to-date with the latest flight information by sending free alerts to your mobile device or email. Additionally, our cutting-edge mobile apps let iPhone and Android users the capability to receive status reports and review baggage and gate claim details on their mobile devices. You can even book hotels or car rentals to go along with your St. Louis to Key West flights or view your itinerary using these useful and easy-to-use apps.

Orbitz booking discounts for St. Louis to Key West flights

Orbitz can remember your information, including numbers your frequent flyer and airline loyalty memberships, so you don’t have to re-enter information when you book your flights from St. Louis to Key West or other flights. Not only does this make booking flights a breeze, you no longer have to go through the hassle of looking up your frequent flyer numbers to add them to your flight reservation.

Frequently asked questions

Am I able to catch a flight from St. Louis to Key West now?
Our Covid-19 Travel Advisor can answer all your questions about current quarantine requirements and travel restrictions when taking a flight from St. Louis to Key West.
What is the shortest flight from St. Louis to Key West?
From St. Louis, the distinctive sights and sounds of Key West are at least 3 hours and 16 minutes away. Book your favorite seat, or perhaps even upgrade to one with extra legroom, and get to your destination in comfort.
If I am not able to travel due to COVID-19, can I cancel my flight to Key West?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Key West have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Key West with flexible change policies?
In most cases you’ll have the option to reschedule your flight to Key West without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2020 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data the cheapest month to fly is August. Perfect for those who need a weekend getaway, or just a break from it all before the weather changes. Be aware that the most expensive time to fly is the height of summer, with ticket prices peaking in the month of June.
How can I save money on flights?
To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you’ll generally get a much better deal. Those who tried this on Orbitz in 2020 saved up to 45% on their airfares. Get mixing and matching today!

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.