Cheap flights from RSW to SAN (Southwest Florida Intl. to San Diego Intl.)

Choose two or more items and save on your trip:

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from RSW to SAN starting at $155 One Way, $278 Round Trip

Prices starting at $278 for return flights and $155 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort
Sheraton San Diego Resort
4 out of 5
1380 Harbor Island Dr, San Diego, CA
The price is $235 per night from May 12 to May 13
$235
includes taxes & fees
$204 per night
May 12 - May 13
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 5 restaurants, and a marina. Our guests praise the pool and the restaurant in ...
8/10 Very Good! (2,615 reviews)
"No view"

Reviewed on Apr 28, 2025

Sheraton San Diego Resort
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is $176 per night from May 11 to May 12
$176
includes taxes & fees
$152 per night
May 11 - May 12
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,676 reviews)
"Room furnishings need updating view from room often blocked by cruise ships one roll of toilet tissue per day"

Reviewed on Apr 26, 2025

Wyndham San Diego Bayside
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
The price is $145 per night from Apr 30 to May 1
$145
includes taxes & fees
$129 per night
Apr 30 - May 1
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,550 reviews)
"Enjoyed our stay and will stay again"

Reviewed on Apr 28, 2025

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

San Diego Mission Bay Resort
San Diego Mission Bay Resort
4 out of 5
1775 E Mission Bay Dr, San Diego, CA
The price is $269 per night from Apr 30 to May 1
$269
includes taxes & fees
$239 per night
Apr 30 - May 1
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
8.2/10 Very Good! (1,193 reviews)
"My kids loved this place. So much to do! Will definitely come back! Very clean rooms and it smelled so clean walking throughout the hallway!"

Reviewed on Apr 26, 2025

San Diego Mission Bay Resort
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
The price is $145 per night from Apr 30 to May 1
$145
includes taxes & fees
$129 per night
Apr 30 - May 1
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,550 reviews)
"Enjoyed our stay and will stay again"

Reviewed on Apr 28, 2025

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is $176 per night from May 11 to May 12
$176
includes taxes & fees
$152 per night
May 11 - May 12
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,676 reviews)
"Room furnishings need updating view from room often blocked by cruise ships one roll of toilet tissue per day"

Reviewed on Apr 26, 2025

Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is $176 per night from May 11 to May 12
$176
includes taxes & fees
$152 per night
May 11 - May 12
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,676 reviews)
"Room furnishings need updating view from room often blocked by cruise ships one roll of toilet tissue per day"

Reviewed on Apr 26, 2025

Wyndham San Diego Bayside
Sheraton San Diego Resort
Sheraton San Diego Resort
4 out of 5
1380 Harbor Island Dr, San Diego, CA
The price is $235 per night from May 12 to May 13
$235
includes taxes & fees
$204 per night
May 12 - May 13
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 5 restaurants, and a marina. Our guests praise the pool and the restaurant in ...
8/10 Very Good! (2,615 reviews)
"No view"

Reviewed on Apr 28, 2025

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 out of 5
1955 San Diego Ave, San Diego, CA
The price is $176 per night from May 11 to May 12
$176
includes taxes & fees
$153 per night
May 11 - May 12
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
8.8/10 Excellent! (1,003 reviews)
"Very comfortable and convenient location. Super friendly staff."

Reviewed on Apr 28, 2025

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn
Pleasant Inn
2.5 out of 5
5550 Clairemont Mesa Blvd, San Diego, CA
The price is $111 per night from Apr 30 to May 1
$111
includes taxes & fees
$99 per night
Apr 30 - May 1
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.4/10 Very Good! (1,008 reviews)
"It would’ve been nice to offer at least a continental breakfast. Also a pool or hot tub would be nice here"

Reviewed on Apr 27, 2025

Pleasant Inn
E-Z 8 Motel Old Town
E-Z 8 Motel Old Town
2.5 out of 5
4747 Pacific Highway, San Diego, CA
The price is $75 per night from Apr 30 to May 1
$75
includes taxes & fees
$66 per night
Apr 30 - May 1
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.2/10 (2,030 reviews)
"The stay was excellent"

Reviewed on Apr 25, 2025

E-Z 8 Motel Old Town
Kings Inn San Diego
Kings Inn San Diego
2.5 out of 5
1333 Hotel Cir S, San Diego, CA
The price is $112 per night from Apr 30 to May 1
$112
includes taxes & fees
$100 per night
Apr 30 - May 1
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.6/10 Excellent! (3,221 reviews)
"Had a short; but good time. Amigo’s restaurant was awesome as usual"

Reviewed on Apr 27, 2025

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel
Bahia Resort Hotel
3.5 out of 5
998 W Mission Bay Dr, San Diego, CA
The price is $269 per night from Apr 30 to May 1
$269
includes taxes & fees
$238 per night
Apr 30 - May 1
Book a stay at this beach resort in San Diego. Enjoy free parking, a beach locale, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
8.6/10 Excellent! (1,523 reviews)
"Nice place, good location. Easy parking"

Reviewed on Apr 20, 2025

Bahia Resort Hotel
The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is $179 per night from Apr 30 to May 1
$179
includes taxes & fees
$159 per night
Apr 30 - May 1
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,347 reviews)
"Super nice location!"

Reviewed on Apr 26, 2025

The Dana on Mission Bay
Catamaran Resort and Spa
Catamaran Resort and Spa
4 out of 5
3999 Mission Boulevard, San Diego, CA
The price is $284 per night from May 5 to May 6
$284
includes taxes & fees
$247 per night
May 5 - May 6
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (1,005 reviews)

Families like: Outdoor pool, game room, on the beach, bicycle rentals

Travelers say...
"This resort was really wonderful. Very tropical feel inside and out. Quiet area close to the bay and ocean. The staff were all very nice and helpful. I look forward to my next stay with kids! Everyone should stop and say hi to Chadwick. :)"

Reviewed on Apr 25, 2025

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

RSW to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
RSW Address & GPS
Address:
11000 Terminal Access Road
Fort Myers FL,
United States
IATA Code:
RSW
Longitude:
-81.755263
Latitude:
26.527887
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Am I able to catch a flight from Fort Myers, FL Airport (RSW-Southwest Florida Intl.) to San Diego, CA Airport (SAN-San Diego Intl.) now?
If you’re puzzled about quarantine and travel restrictions when flying from Fort Myers, FL Airport (RSW-Southwest Florida Intl.) to San Diego, CA Airport (SAN-San Diego Intl.), go right to the Covid-19 Travel Advisor.
Are there non-stop flights from RSW to San Diego, CA Airport (SAN-San Diego Intl.)?
Traveling from Fort Myers, FL Airport (RSW-Southwest Florida Intl.) to San Diego, CA Airport (SAN-San Diego Intl.) means you’re going to have to swap planes. But hey — it’s not all bad. Southwest Airlines, United Airlines and American Airlines offer flights with a single stopover.
What is the shortest flight from RSW to San Diego Intl. Airport (SAN)?
From Edison Park Historic District, the distinctive sights and sounds of Leucadia are 7 hours and 7 minutes away. Make sure you choose your favorite seat, or perhaps even upgrade to one with extra legroom, and travel to your destination in comfort.
How many hours flight from Southwest Florida Intl. Airport (RSW) to San Diego Intl. Airport (SAN)?
On average, it takes 7 hours and 12 minutes to journey from Southwest Florida Intl. Airport to San Diego Airport. You’ll be in the air for quite some time, so take some entertainment, like an audiobook or some crossword puzzles.
If I am not able to travel due to COVID-19, can I cancel my flight to San Diego, CA Airport (SAN-San Diego Intl.)?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to San Diego, CA Airport (SAN-San Diego Intl.) have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to San Diego, CA Airport (SAN-San Diego Intl.) with flexible change policies?
In most cases you’ll have the option to reschedule your flight to San Diego, CA Airport (SAN-San Diego Intl.) without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What airlines have the most flights from Southwest Florida Intl. Airport (RSW) to San Diego, CA Airport (SAN-San Diego Intl.)?
You’ll have to make one or more stopovers if you need to get from Fort Myers, FL Airport (RSW-Southwest Florida Intl.) to San Diego, CA Airport (SAN-San Diego Intl.). Right now, you won’t find any airlines that offer direct flights on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.