$455 Cheap flight deals from Sikeston (STL) to St. Louis (STL)

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Airfares from $455 One Way, Round Trip from Sikeston to St. Louis

Prices starting at for return flights and $455 for one-way flights to St. Louis were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

St. Louis economy flight packages

Price found within the past 48 hours. Click for updated prices.
Capitol Plaza Hotel Jefferson City
3.5-star property

Capitol Plaza Hotel Jefferson City

6.8/10 (1,002 reviews)

Jun 19 - Jun 22

3 night stay

St. Louis (STL) to St. Louis (STL)

American Airlines • Non-stop • Coach

St. Louis (STL) to St. Louis (STL)

Southwest Airlines • Non-stop • Coach
per person
found 1 day ago
Room was very nice. Balcony overlooking atrium was great. Housekeeping never came around to check on needs. A good value.

Reviewed on Sep 29, 2024

The Wildwood Hotel
3.5-star property

The Wildwood Hotel

9/10 Wonderful! (1,464 reviews)

Jun 19 - Jun 22

3 night stay

St. Louis (STL) to St. Louis (STL)

American Airlines • Non-stop • Coach

St. Louis (STL) to St. Louis (STL)

Southwest Airlines • Non-stop • Coach
Save 100% on your flight
per person
found 1 day ago
The staff at this property were incredible. Everyone we talked to was friendly and helpful. I even left something of value behind and they had it shipped to me and I am ever so grateful. The room and the amenities were great and the hotel is in an area that feels safe and has a walking path nearby and also shopping and dining. We would definitely stay here again.

Reviewed on Apr 21, 2025

The Knight Center at Washington University
2.5-star property

The Knight Center at Washington University

9.4/10 Exceptional! (266 reviews)

Jun 19 - Jun 22

3 night stay

St. Louis (STL) to St. Louis (STL)

American Airlines • Non-stop • Coach

St. Louis (STL) to St. Louis (STL)

Southwest Airlines • Non-stop • Coach
per person
found 1 day ago
Overall good experience

Reviewed on Oct 4, 2024

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More About Flying To St. Louis from Sikeston

Route Information for Flights from Sikeston to St. Louis

Origin Airport IATA Code
STL
Destination Airport IATA Code
STL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Sikeston to St. Louis

For the best travel experience from Sikeston to St. Louis domestic and international travelers everywhere choose Orbitz for guaranteed low prices and cutting-edge mobile tools.

Convenient Low-Cost Travel

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At Orbitz you can benefit from low cost travel and have your loyalty rewarded on certain types of Sikeston to St. Louis flights. All you need to do is enter you frequent flyer number when booking and rack up your rewards through Orbitz online on the Traveler Information page for use on future flights. You can even add your frequent flyer number to an existing reservation to start the ball rolling.

Frequently asked questions

Are there non-stop flights from Sikeston to St. Louis?
Yes, Cape Air flies direct from Sikeston to St. Louis, so you’ll be embarking on your fantastic adventure in next to no time.
What is the shortest flight from Sikeston to St. Louis?
It can zip by in as little as 50 minutes. If you’re a firm believer that your vacation hours should be spent ‘vacationing’ rather than flying, you’ll enjoy the trip from Sikeston to St. Louis.
What airlines fly from Sikeston to St. Louis most frequently?
Cape Air is the most frequent flyer along this route. This top-rated air carrier operates 104 flights from Marion, IL (MWA-Williamson County Regional) to St. Louis, MO (STL-Lambert-St. Louis Intl.) each month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.