$60 Cheap flight deals from Detroit (DTT) to St. Louis (STL)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Detroit to St. Louis

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, May 2 - Sat, May 10
FNT
Bishop Intl.
STL
Lambert-St. Louis Intl.
$317 Roundtrip, found 21 hours ago
$317
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Fri, May 2 from Bishop Intl. to Lambert-St. Louis Intl., returning Sat, May 10, priced at $317 found 21 hours ago
Sun, May 4 - Fri, May 9
DTW
Detroit Metropolitan Wayne County
STL
Lambert-St. Louis Intl.
$589 Roundtrip, found 1 day ago
$589
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, May 4 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Fri, May 9, priced at $589 found 1 day ago

Airfares from $60 One Way, $120 Round Trip from Detroit to St. Louis

Prices starting at $120 for return flights and $60 for one-way flights to St. Louis were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Aug 1 - Sun, Aug 3
DTW
Detroit
STL
St. Louis
$120 Roundtrip, found 2 hours ago
$120
Roundtrip
found 2 hours ago
Select Spirit Airlines flight, departing Fri, Aug 1 from Detroit to St. Louis, returning Sun, Aug 3, priced at $120 found 2 hours ago
Fri, Jun 13 - Sun, Jun 15
DTW
Detroit
STL
St. Louis
$121 Roundtrip, just found
$121
Roundtrip
just found
Select Spirit Airlines flight, departing Fri, Jun 13 from Detroit to St. Louis, returning Sun, Jun 15, priced at $121 just found
Fri, Aug 8 - Sun, Aug 10
DTW
Detroit
STL
St. Louis
$140 Roundtrip, found 2 days ago
$140
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Fri, Aug 8 from Detroit to St. Louis, returning Sun, Aug 10, priced at $140 found 2 days ago
Thu, Jul 17 - Mon, Jul 21
DTW
Detroit
STL
St. Louis
$152 Roundtrip, found 2 hours ago
$152
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Jul 17 from Detroit to St. Louis, returning Mon, Jul 21, priced at $152 found 2 hours ago
Thu, Jul 17 - Mon, Jul 21
DTW
Detroit
STL
St. Louis
$160 Roundtrip, found 2 hours ago
$160
Roundtrip
found 2 hours ago
Select Southwest Airlines flight, departing Thu, Jul 17 from Detroit to St. Louis, returning Mon, Jul 21, priced at $160 found 2 hours ago

St. Louis economy flight packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
3.5-star property

The Wildwood Hotel

9/10 Wonderful! (1,464 reviews)

May 26 - May 28

2 night stay

Detroit (DTW) to St. Louis (STL)

Delta • Coach

St. Louis (STL) to Detroit (DTW)

American Airlines • Coach
per person
found 1 day ago
The staff at this property were incredible. Everyone we talked to was friendly and helpful. I even left something of value behind and they had it shipped to me and I am ever so grateful. The room and the amenities were great and the hotel is in an area that feels safe and has a walking path nearby and also shopping and dining. We would definitely stay here again.

Reviewed on Apr 21, 2025

Lodge Of Four Seasons Golf Resort, Marina & Spa
4.0-star property

Lodge Of Four Seasons Golf Resort, Marina & Spa

7.2/10 Good! (1,005 reviews)

May 29 - Jun 3

5 night stay

Detroit (DTW) to St. Louis (STL)

American Airlines • Non-stop roundtrip • Coach
per person
found 1 day ago
Very quiet here this week. They have me a free room upgrade!

Reviewed on Jan 16, 2025

Days Inn by Wyndham Osage Beach Lake of the Ozarks
2.0-star property

Days Inn by Wyndham Osage Beach Lake of the Ozarks

7.2/10 Good! (945 reviews)

May 29 - Jun 3

5 night stay

Detroit (DTW) to St. Louis (STL)

American Airlines • Non-stop roundtrip • Coach
per person
found 1 day ago
The staff members were extremely polite and helpful. We also thought that the hotel was very clean, and we were impressed.

Reviewed on Jun 28, 2022

Don't see what you're looking for?
See all available trips from Detroit to St. Louis
View all trips

More About Flying To St. Louis from Detroit

Route Information for Flights from Detroit to St. Louis

Origin Airport IATA Code
DTT
Destination Airport IATA Code
STL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Cheap Flights from Detroit to St Louis

Detroit Metro Airport

The Orbitz.com website makes it easy to find cheap flights from Detroit to any destination. The Detroit Metro Airport is located at 9000 Middlebelt Road, approximately 21 miles from downtown Detroit. Twelve airlines service the airport, including Delta Airlines, Frontier, Air Tran and American Airlines. When you use Orbitz.com to book your flight, the website searches flights from all available airlines so you can choose a flight with cheap tickets.

Parking and Transportation

The Detroit Metro Airport offers long-term parking for $10 per day. It also runs complimentary shuttle services from the parking lots to the airport terminals. If you're traveling for more than four days, it's cheaper to take a cab to the airport. Cab fare from downtown Detroit costs $44.50. If you need access to a vehicle when you arrive at your destination, you can reserve a rental car using the Orbitz.com website. This way, you can get from the airport to your hotel without relying on public transportation.

Dining at the Airport

There are a variety of restaurants located at the airport including Chili's, Diego's Mexican Cantina, Detroit 500 and Fuddruckers. When you book your flight using Orbitz.com, you have plenty of time to grab a quick meal before your flight, because your travel arrangements are made before you arrive at the airport. The Orbitz.com website does more than find cheap flights from Detroit; it has all the tools you need to plan your entire trip.

Lambert-St. Louis International Airport

Allow Orbitz.com to help you book flights to St. Louis. Lambert-St.Louis International Airport is located 10 miles northwest of St. Louis. Over 13 million passengers pass through the airport each year. It is the largest airport in the state of Missouri and services 255 daily departures to over 90 cities, domestically and internationally. Southwest Airlines is based out of Lambert, and Air Canada, Alaska Airlines, Cape Air, Delta and American Airlines all have major hubs at Lambert. You can use Orbitz.com to book bargain tickets on your next trip to the St. Louis area.

St. Louis International Airport Transportation

St. Louis International Airport offers a variety of transportation services for the busy traveler. Shuttle services, rental cars, and public transportation are available at the airport. Go Best Express Airport Shuttle is a popular shuttle service for group transportation. One-way fares start at $17. The MetroLink is St. Louis' rail system and operates 37 stations throughout the city. One-way fares cost $2.

St. Louis Weather

St. Louis has distinct seasons. Summers are hot, and temperatures can get as high as 90 degrees F. Spring is usually a rainy season for St. Louis, so it is best to pack an umbrella for your trip during March, April and May. Fall is usually mild, with temperatures averaging 57 degrees F. Winters can be freezing, with temperature falling to 20 degrees F. Bring a warm coat and boots during winter trips to St. Louis.

Popular Attractions in St. Louis

St. Louis offers a variety of attractions for visitors. Some popular attractions include the famous Gateway Arch, Six Flags of St. Louis, the Saint Louis Zoo and Forest Park. St. Louis is also home to several theaters, such as the Ferrara Theatre, Fox Theatre, and Grand Center. Some popular museums include the St. Louis Children's Museum and the Beall Mansion Museums. Book flights to St. Louis with the help of Orbitz.com to visit these popular attractions.

Frequently asked questions

Are there non-stop flights from Detroit to St. Louis?
There are a couple of airlines that fly directly from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Lambert Field. Book now with Delta or Southwest Airlines.
What is the shortest flight from Detroit to St. Louis?
Keep that binge-watch you had planned for your hotel room, because the journey from Detroit to St. Louis can take as little as 2 hours and 26 minutes.
What airlines fly from Detroit to St. Louis most frequently?
Delta (DL) is one of the carriers with the most flights from DTW to STL. It offers 117 flights on this route each month. Taking off on a vacation is one of life’s biggest pleasures, and this carrier will get you where you need to go. If you need a few more options, check out the prices with Southwest Airlines (WN), which operates 4 flights from Detroit to St. Louis every month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.