$73 Cheap flight deals from Louisville (SDF) to St. Louis (STL)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Airfares from $73 One Way, Round Trip from Louisville to St. Louis

Prices starting at for return flights and $73 for one-way flights to St. Louis were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

St. Louis economy flight packages

Price found within the past 48 hours. Click for updated prices.
Days Inn by Wyndham Rolla
2.5-star property

Days Inn by Wyndham Rolla

8.2/10 Very Good! (1,003 reviews)

Jun 5 - Jun 9

4 night stay

Louisville (SDF) to St. Louis (STL)

Southwest Airlines • Non-stop roundtrip • Coach
per person
found 13 hours ago
Perfect value for short stay

Reviewed on Mar 19, 2025

Baymont by Wyndham Rolla
2.5-star property

Baymont by Wyndham Rolla

8/10 Very Good! (1,005 reviews)

Jun 5 - Jun 9

4 night stay

Louisville (SDF) to St. Louis (STL)

Southwest Airlines • Non-stop roundtrip • Coach
per person
found 13 hours ago
Very clean hotel a little close to the interstate so some noise, would recommend lake view. close to just about everything if you have a car.

Reviewed on Apr 1, 2025

Super 8 by Wyndham Cuba
2.0-star property

Super 8 by Wyndham Cuba

8.8/10 Excellent! (902 reviews)

Jun 5 - Jun 9

4 night stay

Louisville (SDF) to St. Louis (STL)

Southwest Airlines • Non-stop roundtrip • Coach
per person
found 13 hours ago
Very friendly at check in, we’ll lite and feels safe.

Reviewed on Apr 7, 2021

Don't see what you're looking for?
See all available trips from Louisville to St. Louis
View all trips

More About Flying To St. Louis from Louisville

Route Information for Flights from Louisville to St. Louis

Origin Airport IATA Code
SDF
Destination Airport IATA Code
STL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Louisville to St. Louis

The best fares for Louisville to St. Louis flights are always found on Orbitz. With superior discounts and the latest innovations in mobile access, your ideal trip starts with Orbitz.

The Easy Way to Plan Travel Cheaply

We provide access to many low-cost vacation packages and travelers can mix and match airlines when scheduling their flights for the best prices and flight times. Finding cheap tickets on flights from Louisville to St. Louis is easy when you make Orbitz your #1 travel planner.

Book Louisville to St. Louis Flights With Mobile Apps

Our iPhone and Android mobile apps can be used to compare and book flights from Louisville to St. Louis. These apps are perfect for checking the status of flights, gate and baggage claims details, car rental rates, and for receiving alerts on special savings that are exclusive to mobile users. Mobile app users can even score great rates when booking hotel rooms. You can compare hotels, virtually view photo galleries, and check out user reviews using the app, as well as find out which ones are closest to you.

Orbitz also offers free travel updates that are sent to your email or mobile phone that notifies you of booking changes, disruptions in service, or delayed flights.

Increase Your Rewards While Enjoying Super Low Rates

Boost your points or miles for your frequent flyer program on certain Louisville to St. Louis flights. Simply provide your frequent flyer information when booking flights from Louisville to St. Louis with Orbitz and get both a low fare and travel rewards. You can enter this information in your Orbitz account profile for easy remembering in future bookings.

Frequently asked questions

What is the shortest flight from Louisville to St. Louis?
If conditions are good and all goes as planned, you could be coming in to land at Lambert-St. Louis Intl. Airport (STL) from Louisville Muhammad Ali Intl. Airport in only 2 hours and 25 minutes. With such a speedy flight time, consider taking just carry-on luggage.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.