$149 Cheap flight deals from Des Moines (DSM) to Destin (VPS)
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Airfares from $149 One Way, $273 Round Trip from Des Moines to Destin
Prices starting at $273 for return flights and $149 for one-way flights to Destin were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Destin economy flight packages
Sandestin Golf and Beach Resort
May 26 - May 30
Des Moines (DSM) to Fort Walton Beach (VPS)
Reviewed on Mar 24, 2025
Destin Holiday Beach Resort
May 28 - May 31
Des Moines (DSM) to Fort Walton Beach (VPS)
Reviewed on Jul 4, 2021
More About Flying To Destin from Des Moines
Route Information for Flights from Des Moines to Destin
Origin Airport IATA Code | DSM |
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Destination Airport IATA Code | VPS |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Des Moines to Destin
It has never been easier to find cheap Des Moines to Destin flights. Orbitz has some of the best deals around to save you more money on your flight, hotel, and vacation package for the trip you have been waiting for.
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Get the Best Deals on Des Moines to Destin Flights
Finding great deals on flights from Des Moines to Destin is a snap with Orbitz. With our guaranteed low prices, you don’t have to worry if you are getting the best prices on air tickets, hotels, and cruises. And with all that money you saved, you can enjoy your Destin vacation even more.
Pile Up Miles With Discount Air Tickets
Not only can you find great bargains on Des Moines to Destin flights, but you can rack up frequent flyer miles on the flights too. Enter your frequent flyer number on qualified flights when booking for Orbitz to see the miles pile up in your account.
Flight Alerts Keep You Informed
Stay on top of the latest updates for flights from Des Moines to Destin. We send you free email and mobile alerts to keep you informed about delays to Des Moines to Destin flights.
Flights from Des Moines
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.