$40 Cheap flight deals from Denver (DEN) to St. Louis (STL)

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This Weekend's Flight Deals from Denver to St. Louis

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Apr 26 - Sun, Apr 27
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$318 Roundtrip, found 7 hours ago
$318
Roundtrip
found 7 hours ago
Select Frontier Airlines flight, departing Sat, Apr 26 from Denver Intl. to Lambert-St. Louis Intl., returning Sun, Apr 27, priced at $318 found 7 hours ago

Airfares from $40 One Way, $78 Round Trip from Denver to St. Louis

Prices starting at $78 for return flights and $40 for one-way flights to St. Louis were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, May 7 - Sat, May 10
DEN
Denver
STL
St. Louis
$78 Roundtrip, found 1 day ago
$78
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, May 7 from Denver to St. Louis, returning Sat, May 10, priced at $78 found 1 day ago
Wed, Jun 4 - Sat, Jun 7
DEN
Denver
STL
St. Louis
$110 Roundtrip, found 2 hours ago
$110
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Wed, Jun 4 from Denver to St. Louis, returning Sat, Jun 7, priced at $110 found 2 hours ago
Wed, May 14 - Sat, May 17
DEN
Denver
STL
St. Louis
$116 Roundtrip, found 7 hours ago
$116
Roundtrip
found 7 hours ago
Select Frontier Airlines flight, departing Wed, May 14 from Denver to St. Louis, returning Sat, May 17, priced at $116 found 7 hours ago
Mon, Jun 9 - Tue, Jun 10
DEN
Denver
STL
St. Louis
$186 Roundtrip, found 6 hours ago
$186
Roundtrip
found 6 hours ago
Select Southwest Airlines flight, departing Mon, Jun 9 from Denver to St. Louis, returning Tue, Jun 10, priced at $186 found 6 hours ago
Tue, Jun 3 - Wed, Jun 4
DEN
Denver
STL
St. Louis
$214 Roundtrip, found 3 days ago
$214
Roundtrip
found 3 days ago
Select United flight, departing Tue, Jun 3 from Denver to St. Louis, returning Wed, Jun 4, priced at $214 found 3 days ago

St. Louis economy flight packages

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield
3.0-star property

Hilton Garden Inn Chesterfield

8.2/10 Very Good! (735 reviews)

Jun 3 - Jun 5

2 night stay

Denver (DEN) to St. Louis (STL)

Southwest Airlines • Non-stop roundtrip • Coach
per person
found 11 hours ago
Great stay great service

Reviewed on Apr 8, 2025

The Wildwood Hotel
3.5-star property

The Wildwood Hotel

9/10 Wonderful! (1,464 reviews)

Jun 3 - Jun 5

2 night stay

Denver (DEN) to St. Louis (STL)

Southwest Airlines • Non-stop roundtrip • Coach
per person
found 11 hours ago
The staff at this property were incredible. Everyone we talked to was friendly and helpful. I even left something of value behind and they had it shipped to me and I am ever so grateful. The room and the amenities were great and the hotel is in an area that feels safe and has a walking path nearby and also shopping and dining. We would definitely stay here again.

Reviewed on Apr 21, 2025

Sonesta ES Suites St. Louis - Chesterfield
3.0-star property

Sonesta ES Suites St. Louis - Chesterfield

8/10 Very Good! (1,007 reviews)

Jun 4 - Jun 8

4 night stay

Denver (DEN) to St. Louis (STL)

Frontier Airlines • Coach

St. Louis (STL) to Denver (DEN)

Delta • Coach
per person
found 5 hours ago
Front desk wasnt too welcoming or friendly. I doubt i ever return

Reviewed on Mar 3, 2025

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More About Flying To St. Louis from Denver

Route Information for Flights from Denver to St. Louis

Origin Airport IATA Code
DEN
Destination Airport IATA Code
STL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Flying from Denver to St. Louis

When you’re planning a relaxing vacation from Denver, St. Louis offers just the right level of cultural contrast for an exciting trip. As you plan each part of your journey, use Orbitz.com to find flights from Denver to St Louis, and then check out the special deals on hotels, rental cars, and local transportation.

Flying out of Denver

Denver International Airport is located about twenty-eight miles outside of the downtown area. The best deal on airport parking can be found at the Pikes Peak Shuttle Lot. If you’re looking for luxury, choose the valet parking service in the Garage East or Garage West. You can also get to the airport by taxi, commuter shuttle, or the Regional Transportation District bus system. If you live near any of the ski resorts around Denver, check into shared-ride services from the area’s mountain carriers.

Highlights of St. Louis

Your flight into Missouri will arrive at Lambert-St. Louis International Airport. If you’re renting a car, the fifteen-mile drive will take about thirty minutes. Public transportation options at the airport include the excellent MetroLink service. Shared shuttles, such as the Go Best Express service, are a good option if you need assistance carrying your bags. When you arrive downtown, check out some of St. Louis’ most popular sights, including the world-famous Gateway Arch, the spectacular Cathedral Basilica of Saint Louis, and the Magic House St. Louis Children’s Museum. The best time to visit is during the spring and fall, when temperatures average 60°F. Summers average 75°F, and winter days frequently drop to 30°F or lower.

Traveling to St. Louis

With its urban delights and charming locals, St. Louis is certain to draw you in and win you over. Whether you’re traveling for a quick business trip or vacationing with the whole family, Orbitz.com can help you find the best prices on flights from Denver to St. Louis so that you can relax and enjoy the journey.

Frequently asked questions

Are there non-stop flights from Denver to St. Louis?
Yep, your unforgettable vacation is just a single flight away. Fantastic news, isn’t it? Travel comfortably aboard one of the 3 carriers that fly straight from Denver, CO (DEN-Denver Intl.) to Lambert Field. Popular picks include:

  • Southwest Airlines
  • United Airlines
  • Frontier Airlines

What is the shortest flight from Denver to St. Louis?
The trip from Denver to St. Louis can be as quick as 2 hours and 51 minutes. With an easy flight time like this, why not book an impromptu getaway?
What airlines fly from Denver to St. Louis most frequently?
Southwest Airlines (WN) is one of the airlines with the most flights from Denver Intl. Airport (DEN) to Lambert-St. Louis Intl. Airport (STL). It offers 160 flights on this route each month. Going on vacation is one of life’s biggest pleasures, and this airline will get you where you need to go. If you need some more options, look up the cost of tickets with United Airlines (UA), which has 121 flights from Denver to St. Louis every month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.