Spa Resorts in Southeast Missouri, MO
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Featured Southeast Missouri Spa Resorts & Hotels

Crown Pointe Lodge, BW Signature Collection
4245 Hunt Rd, Farmington, MO
Free Cancellation
Reserve now, pay when you stay
The price is $143 per night
$143
includes taxes & fees
$126 per night
Apr 27 - Apr 28
Crown Pointe Lodge, BW Signature Collection features a golf course, an indoor pool, and a gym. There's free parking and an area shuttle. The 24-hour front desk has staff always at the ready. Other amenities at this golf hotel include free WiFi in public areas, a hot tub, and a business center.
Pool
Hot Tub

Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $107 per night
$107
includes taxes & fees
$94 per night
Apr 27 - Apr 28
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Drury Inn & Suites Hayti Caruthersville
1317 E Highway 84, Hayti, MO
Free Cancellation
Reserve now, pay when you stay
The price is $123 per night
$123
includes taxes & fees
$108 per night
Apr 13 - Apr 14
At Drury Inn & Suites Hayti Caruthersville, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Drury Inn & Suites Jackson MO
225 Drury Lane, Jackson, MO
Free Cancellation
Reserve now, pay when you stay
The price is $95 per night
$95
includes taxes & fees
$90 per night
Apr 7 - Apr 8
Guests of Drury Inn & Suites Jackson MO have access to an indoor pool, a gym, and free WiFi in public areas. There's free parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Drury Inn & Suites Poplar Bluff
2220 N Westwood Blvd, Poplar Bluff, MO
Free Cancellation
Reserve now, pay when you stay
The price is $117 per night
$117
includes taxes & fees
$103 per night
Apr 17 - Apr 18
Drury Inn & Suites Poplar Bluff features an indoor pool, an outdoor pool, and a gym. A stay here includes free parking. Front-desk staff can answer questions 24/7, and assist with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a hot tub, and meeting rooms.
Pool
Hot Tub

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $107 per night
$107
includes taxes & fees
$94 per night
Apr 7 - Apr 8
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a conference center.
Pool
Hot Tub

Eagle Inn Charleston
2811 East Marshall Street, Charleston, MO
Free Cancellation
Reserve now, pay when you stay
The price is $61 per night
$61
includes taxes & fees
$55 per night
May 2 - May 3
Guests staying at Eagle Inn Charleston enjoy a gym, free WiFi in public areas, and a vending machine. There's free parking if you drive. The 24-hour front desk has staff always at the ready.
Pet friendly
Parking included

Hampton Inn Farmington
850 Valley Creek Dr, Farmington, MO
Free Cancellation
Reserve now, pay when you stay
The price is $135 per night
$135
includes taxes & fees
$118 per night
Apr 13 - Apr 14
Guests staying at Hampton Inn Farmington enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include a hot tub, meeting rooms, and a 24-hour business center.
Pool
Hot Tub

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
4800 U.S. Highway 67, De Soto, MO
Free Cancellation
The price is $183 per night
$183
includes taxes & fees
$172 per night
Apr 6 - Apr 7
At Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG, guests have access to a gym, a sauna, and outdoor tennis courts. If you decide to drive, there's free parking. Front-desk staff can assist with securing valuables and luggage storage. Other amenities at this family-friendly aparthotel include a business center, a seasonal outdoor pool, and an arcade/game room.
Pool
Parking included

Super 8 by Wyndham Perryville
1119 Vincent Dr, Perryville, MO
Free Cancellation
Reserve now, pay when you stay
The price is $79 per night
$79
includes taxes & fees
$69 per night
May 4 - May 5
Guests staying at Super 8 by Wyndham Perryville enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a business center, a meeting room, and free newspapers.
Pool
Breakfast included

Super 8 by Wyndham Pevely
1711 Highway Z, Pevely, MO
At Super 8 by Wyndham Pevely, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included
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See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southeast Missouri hotels essential information
Accommodation | 554 hotels |
---|---|
Lowest Price | $61 |
Highest Price | $183 |
Popular hotels | Crown Pointe Lodge, BW Signature Collection, Drury Inn & Suites Cape Girardeau, Drury Inn & Suites Hayti Caruthersville, Drury Inn & Suites Jackson MO, Drury Inn & Suites Poplar Bluff, Drury Plaza Hotel Cape Girardeau Conference Center, Eagle Inn Charleston, Hampton Inn Farmington, Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG, Super 8 by Wyndham Perryville, Super 8 by Wyndham Pevely |
Recent Spa Resorts & Hotels Reviews

Baymont Inn and Suites by Wyndham Farmington, MO
5/5 Excellent
"Great stay."
A verified traveler stayed at Baymont Inn and Suites by Wyndham Farmington, MO
Posted 2 days ago
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