Cheap flights from MCO to TYS (Orlando Intl. to McGhee Tyson)

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Cheap Flights from MCO to TYS starting at $101 One Way, $228 Round Trip

Prices starting at $228 for return flights and $101 for one-way flights to McGhee Tyson were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, May 29 - Mon, Jun 9
MCO
Orlando
TYS
Knoxville
$228 Roundtrip, found 8 hours ago
$228
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Thu, May 29 from Orlando to Knoxville, returning Mon, Jun 9, priced at $228 found 8 hours ago
Sun, Jun 1 - Thu, Jun 5
MCO
Orlando
TYS
Knoxville
$234 Roundtrip, found 1 day ago
$234
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Jun 1 from Orlando to Knoxville, returning Thu, Jun 5, priced at $234 found 1 day ago
Sun, Jun 1 - Sun, Jun 8
MCO
Orlando
TYS
Knoxville
$234 Roundtrip, found 8 hours ago
$234
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Sun, Jun 1 from Orlando to Knoxville, returning Sun, Jun 8, priced at $234 found 8 hours ago
Sun, May 4 - Sun, May 11
MCO
Orlando
TYS
Knoxville
$243 Roundtrip, found 3 days ago
$243
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sun, May 4 from Orlando to Knoxville, returning Sun, May 11, priced at $243 found 3 days ago
Thu, Mar 5 - Tue, Mar 10
MCO
Orlando
TYS
Knoxville
$249 Roundtrip, found 4 days ago
$249
Roundtrip
found 4 days ago
Select United flight, departing Thu, Mar 5 from Orlando to Knoxville, returning Tue, Mar 10, priced at $249 found 4 days ago

Hotel Ideas near McGhee Tyson

Airport Hotels near McGhee Tyson

La Quinta Inn & Suites by Wyndham Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
2.5 out of 5
126 Cusick Road, Alcoa, TN
The price is $109 per night from Apr 27 to Apr 28
$109
includes taxes & fees
$94 per night
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,405 reviews)
"Excellent check-in experience. Very kind and knowledgeable desk staff."

Reviewed on Apr 21, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport
Hilton Knoxville Airport
3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
The price is $181 per night from May 4 to May 5
$181
includes taxes & fees
$158 per night
May 4 - May 5
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,002 reviews)
"Staff was awesome. Steps to Knoxville airport. Super convenient."

Reviewed on Apr 21, 2025

Hilton Knoxville Airport
Tru by Hilton Alcoa Knoxville Airport
Tru by Hilton Alcoa Knoxville Airport
2.5 out of 5
125 FURROW WAY, Alcoa, TN
The price is $118 per night from May 5 to May 6
$118
includes taxes & fees
$102 per night
May 5 - May 6
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (536 reviews)
"The hotel was clean and well maintained. The staff was very friendly. The breakfast was a good variety of options"

Reviewed on Apr 20, 2025

Tru by Hilton Alcoa Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Knoxville

La Quinta Inn & Suites by Wyndham Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
2.5 out of 5
126 Cusick Road, Alcoa, TN
The price is $109 per night from Apr 27 to Apr 28
$109
includes taxes & fees
$94 per night
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,405 reviews)
"Excellent check-in experience. Very kind and knowledgeable desk staff."

Reviewed on Apr 21, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport
Hilton Knoxville Airport
3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
The price is $181 per night from May 4 to May 5
$181
includes taxes & fees
$158 per night
May 4 - May 5
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,002 reviews)
"Staff was awesome. Steps to Knoxville airport. Super convenient."

Reviewed on Apr 21, 2025

Hilton Knoxville Airport
Best Western Knoxville Airport/Alcoa
Best Western Knoxville Airport/Alcoa
2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $93 per night from Apr 27 to Apr 28
$93
includes taxes & fees
$81 per night
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,000 reviews)
"Everything was super clean, super close to the airport and the staff is super nice"

Reviewed on Apr 20, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Knoxville Hotels With Airport Transportation

La Quinta Inn & Suites by Wyndham Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
2.5 out of 5
126 Cusick Road, Alcoa, TN
The price is $109 per night from Apr 27 to Apr 28
$109
includes taxes & fees
$94 per night
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,405 reviews)
"Excellent check-in experience. Very kind and knowledgeable desk staff."

Reviewed on Apr 21, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
USA Inn
USA Inn
3 out of 5
Alcoa Hwy, 2962, Alcoa, TN
The price is $68 per night from Apr 27 to Apr 28
$68
includes taxes & fees
$59 per night
Apr 27 - Apr 28
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (697 reviews)
"Ac was great, they have a minor roach and prostitution issue, couldn’t sleep without hearing them “working” or waiting outside for people every night."

Reviewed on Oct 6, 2024

USA Inn
Best Western Knoxville Airport/Alcoa
Best Western Knoxville Airport/Alcoa
2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $93 per night from Apr 27 to Apr 28
$93
includes taxes & fees
$81 per night
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,000 reviews)
"Everything was super clean, super close to the airport and the staff is super nice"

Reviewed on Apr 20, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Knoxville Hotels

USA Inn
USA Inn
3 out of 5
Alcoa Hwy, 2962, Alcoa, TN
The price is $68 per night from Apr 27 to Apr 28
$68
includes taxes & fees
$59 per night
Apr 27 - Apr 28
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (697 reviews)
"Ac was great, they have a minor roach and prostitution issue, couldn’t sleep without hearing them “working” or waiting outside for people every night."

Reviewed on Oct 6, 2024

USA Inn
Candlewood Suites Knoxville Airport-Alcoa by IHG
Candlewood Suites Knoxville Airport-Alcoa by IHG
2.5 out of 5
176 Cusick Road, Alcoa, TN
The price is $132 per night from Apr 27 to Apr 28
$132
includes taxes & fees
$114 per night
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Meigs Falls and Palace Theater ...
8.2/10 Very Good! (536 reviews)
"Nice place will come bk in future'"

Reviewed on Apr 20, 2025

Candlewood Suites Knoxville Airport-Alcoa by IHG
Best Western Knoxville Airport/Alcoa
Best Western Knoxville Airport/Alcoa
2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $93 per night from Apr 27 to Apr 28
$93
includes taxes & fees
$81 per night
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,000 reviews)
"Everything was super clean, super close to the airport and the staff is super nice"

Reviewed on Apr 20, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Knoxville

Comfort Suites Knoxville Airport
Comfort Suites Knoxville Airport
2.5 out of 5
140 Cusick Rd, Alcoa, TN
The price is $107 per night from May 4 to May 5
$107
includes taxes & fees
$93 per night
May 4 - May 5
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (660 reviews)
"Close to the airport"

Reviewed on Apr 14, 2025

Comfort Suites Knoxville Airport
Best Western Knoxville Airport/Alcoa
Best Western Knoxville Airport/Alcoa
2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $93 per night from Apr 27 to Apr 28
$93
includes taxes & fees
$81 per night
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,000 reviews)
"Everything was super clean, super close to the airport and the staff is super nice"

Reviewed on Apr 20, 2025

Best Western Knoxville Airport/Alcoa
La Quinta Inn & Suites by Wyndham Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
2.5 out of 5
126 Cusick Road, Alcoa, TN
The price is $109 per night from Apr 27 to Apr 28
$109
includes taxes & fees
$94 per night
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,405 reviews)
"Excellent check-in experience. Very kind and knowledgeable desk staff."

Reviewed on Apr 21, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MCO to TYS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MCO Address & GPS
Address:
One Airport Boulevard
Orlando FL, 32827-4399
United States
IATA Code:
MCO
Longitude:
-81.308301
Latitude:
28.432177
Time Zone:
America/New_York
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York

Frequently asked questions

Am I able to catch a flight from Orlando, FL Airport (MCO-Orlando Intl.) to Knoxville, TN Airport (TYS-McGhee Tyson) now?
Our Covid-19 Travel Advisor can help you with queries about travel restrictions and quarantine when traveling by plane from Orlando, FL Airport (MCO-Orlando Intl.) to Knoxville, TN Airport (TYS-McGhee Tyson).
Are there non-stop flights from MCO to McGhee Tyson Airport (TYS)?
You’re going to need to switch planes if you’re planning to fly from Orlando, FL Airport (MCO-Orlando Intl.) to Knoxville Airport. Numerous companies operate on this route with only one stopover, including American Airlines, Delta and United Airlines.
What is the shortest flight from Orlando Intl. Airport to Knoxville Airport?
Treat yourself to an in-flight wine and get comfy in your seat with a fascinating book or movie. With the journey from Lake Nona Medical City to Old City taking 4 hours and 23 minutes, there’s plenty of time to sit back and enjoy the ride.
How many hours flight from Orlando, FL Airport (MCO-Orlando Intl.) to Knoxville, TN Airport (TYS-McGhee Tyson)?
It usually takes about 4 hours and 30 minutes to go from MCO to TYS. Get through the flight by watching movies and getting stuck into a good book. Alternatively, catch up on some Zs.
If I am not able to travel due to COVID-19, can I cancel my flight to Knoxville, TN Airport (TYS-McGhee Tyson)?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Knoxville, TN Airport (TYS-McGhee Tyson) have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Knoxville, TN Airport (TYS-McGhee Tyson) with flexible change policies?
In most cases you’ll have the option to reschedule your flight to Knoxville, TN Airport (TYS-McGhee Tyson) without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What airlines have the most flights from Orlando Intl. Airport to Knoxville Airport?
Pick up a souvenir, tuck into some takeaway, get the blood flowing again … Airport stopovers don’t have to be annoying! If you’re planning to head between Lake Nona Medical City and Old City, you won’t find any direct flights. Prepare for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.