Cheap flights from DSM to SAN (Des Moines Intl. to San Diego Intl.)

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Cheap Flights from DSM to SAN starting at $61 One Way, $141 Round Trip

Prices starting at $141 for return flights and $61 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Mar 26 - Thu, Apr 3
DSM
Des Moines
SAN
San Diego
$141 Roundtrip, found 1 day ago
$141
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Mar 26 from Des Moines to San Diego, returning Thu, Apr 3, priced at $141 found 1 day ago
Mon, Mar 10 - Mon, Mar 17
DSM
Des Moines
SAN
San Diego
$161 Roundtrip, just found
$161
Roundtrip
just found
Select Frontier Airlines flight, departing Mon, Mar 10 from Des Moines to San Diego, returning Mon, Mar 17, priced at $161 just found
Mon, Apr 14 - Fri, Apr 18
DSM
Des Moines
SAN
San Diego
$180 Roundtrip, found 22 hours ago
$180
Roundtrip
found 22 hours ago
Select Frontier Airlines flight, departing Mon, Apr 14 from Des Moines to San Diego, returning Fri, Apr 18, priced at $180 found 22 hours ago
Mon, Mar 10 - Fri, Mar 14
DSM
Des Moines
SAN
San Diego
$181 Roundtrip, found 18 hours ago
$181
Roundtrip
found 18 hours ago
Select Frontier Airlines flight, departing Mon, Mar 10 from Des Moines to San Diego, returning Fri, Mar 14, priced at $181 found 18 hours ago
Fri, May 9 - Sat, May 24
DSM
Des Moines
SAN
San Diego
$185 Roundtrip, found 3 days ago
$185
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, May 9 from Des Moines to San Diego, returning Sat, May 24, priced at $185 found 3 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort
Sheraton San Diego Resort
4 out of 5
1380 Harbor Island Dr, San Diego, CA
The price is $231 per night from Mar 7 to Mar 8
$231
includes taxes & fees
$205 per night
Mar 7 - Mar 8
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 6 restaurants, and a marina. Our guests praise the pool and the restaurant in ...
8/10 Very Good! (2,560 reviews)
"I really liked the calmness."

Reviewed on Feb 21, 2025

Sheraton San Diego Resort
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is $181 per night from Mar 16 to Mar 17
$181
includes taxes & fees
$161 per night
Mar 16 - Mar 17
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,614 reviews)
"The air conditioning was vary noisy."

Reviewed on Feb 20, 2025

Wyndham San Diego Bayside
Comfort Inn Sea World Area
Comfort Inn Sea World Area
3.5 out of 5
3880 Greenwood St, San Diego, CA
The price is $106 per night from Feb 25 to Feb 26
$106
includes taxes & fees
$95 per night
Feb 25 - Feb 26
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,645 reviews)
Rooms are comfortable
"The hotel was clean, the breakfast not so great! The room was clean and very comfortable!"

Reviewed on Feb 22, 2025

Comfort Inn Sea World Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is $168 per night from Feb 24 to Feb 25
$168
includes taxes & fees
$149 per night
Feb 24 - Feb 25
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 spa tubs. Our guests praise the pool and the restaurant in ...
8.6/10 Excellent! (3,195 reviews)
"Great location, clean property great pool quality and service plus the rooms were excellent condition"

Reviewed on Feb 23, 2025

The Dana on Mission Bay
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is $181 per night from Mar 16 to Mar 17
$181
includes taxes & fees
$161 per night
Mar 16 - Mar 17
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,614 reviews)
"The air conditioning was vary noisy."

Reviewed on Feb 20, 2025

Wyndham San Diego Bayside
Omni San Diego Hotel
Omni San Diego Hotel
4 out of 5
675 L St, San Diego, CA
The price is $241 per night from Mar 15 to Mar 16
$241
includes taxes & fees
$214 per night
Mar 15 - Mar 16
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9/10 Wonderful! (1,843 reviews)
"Nice location and hotel"

Reviewed on Feb 20, 2025

Omni San Diego Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is $181 per night from Mar 16 to Mar 17
$181
includes taxes & fees
$161 per night
Mar 16 - Mar 17
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,614 reviews)
"The air conditioning was vary noisy."

Reviewed on Feb 20, 2025

Wyndham San Diego Bayside
Sheraton San Diego Resort
Sheraton San Diego Resort
4 out of 5
1380 Harbor Island Dr, San Diego, CA
The price is $231 per night from Mar 7 to Mar 8
$231
includes taxes & fees
$205 per night
Mar 7 - Mar 8
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 6 restaurants, and a marina. Our guests praise the pool and the restaurant in ...
8/10 Very Good! (2,560 reviews)
"I really liked the calmness."

Reviewed on Feb 21, 2025

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town, an IHG Hotel
Holiday Inn Express San Diego Airport - Old Town, an IHG Hotel
2.5 out of 5
1955 San Diego Ave, San Diego, CA
The price is $171 per night from Mar 2 to Mar 3
$171
includes taxes & fees
$152 per night
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
8.8/10 Excellent! (1,017 reviews)
"Amazing comfy bed, very clean room with everything you need for a cozy stay, helpful staff, free shuttle to the airport. The only thing was I got a veggie tray from the little market store by reception and the veggies were all spoiled."

Reviewed on Feb 21, 2025

Holiday Inn Express San Diego Airport - Old Town, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn
Pleasant Inn
2.5 out of 5
5550 Clairemont Mesa Blvd, San Diego, CA
The price is $111 per night from Feb 24 to Feb 25
$111
includes taxes & fees
$99 per night
Feb 24 - Feb 25
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.2/10 Very Good! (1,006 reviews)
"Reasonably priced in a convenient location. Staff was pleasant and helpful. Great dining options nearby. Clean. Could use warmer blankets though."

Reviewed on Feb 20, 2025

Pleasant Inn
E-Z 8 Motel Old Town
E-Z 8 Motel Old Town
2.5 out of 5
4747 Pacific Highway, San Diego, CA
The price is $69 per night from Feb 24 to Feb 25
$69
includes taxes & fees
$61 per night
Feb 24 - Feb 25
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.2/10 (2,024 reviews)
"The parking was real sketchy for bigger vehicles"

Reviewed on Feb 19, 2025

E-Z 8 Motel Old Town
Kings Inn San Diego
Kings Inn San Diego
2.5 out of 5
1333 Hotel Cir S, San Diego, CA
The price is $94 per night from Feb 24 to Feb 25
$94
includes taxes & fees
$83 per night
Feb 24 - Feb 25
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.6/10 Excellent! (3,152 reviews)
"Our room had been recently renovated. The bed was comfortable. They have a good family restaurant for breakfast and lunch. Con. They charge for parking."

Reviewed on Feb 22, 2025

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel
Bahia Resort Hotel
3.5 out of 5
998 W Mission Bay Dr, San Diego, CA
The price is $227 per night from Mar 2 to Mar 3
$227
includes taxes & fees
$201 per night
Mar 2 - Mar 3
Book a stay at this beach resort in San Diego. Enjoy free parking, a beach locale, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
8.6/10 Excellent! (1,466 reviews)
"This property was nice, could use some updating. But still nice overall."

Reviewed on Feb 19, 2025

Bahia Resort Hotel
The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is $168 per night from Feb 24 to Feb 25
$168
includes taxes & fees
$149 per night
Feb 24 - Feb 25
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 spa tubs. Our guests praise the pool and the restaurant in ...
8.6/10 Excellent! (3,195 reviews)
"Great location, clean property great pool quality and service plus the rooms were excellent condition"

Reviewed on Feb 23, 2025

The Dana on Mission Bay
Catamaran Resort and Spa
Catamaran Resort and Spa
4 out of 5
3999 Mission Boulevard, San Diego, CA
The price is $257 per night from Mar 24 to Mar 25
$257
includes taxes & fees
$228 per night
Mar 24 - Mar 25
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (1,004 reviews)

Families like: Outdoor pools, game room, on the beach, bicycle rentals

Travelers say...
"Nice property"

Reviewed on Feb 21, 2025

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

DSM to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Am I able to catch a flight from Des Moines, IA Airport (DSM-Des Moines Intl.) to San Diego, CA Airport (SAN-San Diego Intl.) now?
If you’re agonizing over quarantine requirements and travel restrictions when getting a flight from Des Moines, IA Airport (DSM-Des Moines Intl.) to San Diego, CA Airport (SAN-San Diego Intl.), go right to the Covid-19 Travel Advisor.
Are there non-stop flights from DSM to San Diego Airport?
You’re going to have to swap planes if you want to get from Des Moines Intl. Airport (DSM) to San Diego Intl. Airport (SAN). Numerous carriers offer services on this route with just one stopover, including American Airlines, United Airlines and Alaska Airlines.
What is the shortest flight from Des Moines Intl. Airport (DSM) to SAN?
Use the opportunity to sit back and relax on your journey from Downtown Des Moines to Leucadia. The shortest flight time from Des Moines, IA Airport (DSM-Des Moines Intl.) to SAN is 5 hours and 4 minutes, which gives you plenty of time to enjoy a wine or get engrossed in a book.
How many hours flight from Des Moines Intl. Airport to San Diego, CA Airport (SAN-San Diego Intl.)?
From DSM to SAN, you’ll be traveling for around 5 hours and 9 minutes. Settle in, order a glass of wine and take out your noise-canceling headphones. It’s time to binge-watch some awesome TV shows.
If I am not able to travel due to COVID-19, can I cancel my flight to San Diego, CA Airport (SAN-San Diego Intl.)?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to San Diego, CA Airport (SAN-San Diego Intl.) have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to San Diego, CA Airport (SAN-San Diego Intl.) with flexible change policies?
In most cases you’ll have the option to reschedule your flight to San Diego, CA Airport (SAN-San Diego Intl.) without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What airlines have the most flights from DSM to San Diego Intl. Airport (SAN)?
At the moment, there are no airlines that have direct flights from DSM to San Diego, CA Airport (SAN-San Diego Intl.). Don’t panic though! There are numerous single or multi-stop options available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.