$101 Cheap flight deals from Knoxville (TYS) to Des Moines (DSM)

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Airfares from $101 One Way, $225 Round Trip from Knoxville to Des Moines

Prices starting at $225 for return flights and $101 for one-way flights to Des Moines were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Jul 1 - Fri, Jul 11
TYS
Knoxville
DSM
Des Moines
$225 Roundtrip, found 6 days ago
$225
Roundtrip
found 6 days ago
Select United flight, departing Tue, Jul 1 from Knoxville to Des Moines, returning Fri, Jul 11, priced at $225 found 6 days ago
Wed, May 28 - Wed, Jun 4
TYS
Knoxville
DSM
Des Moines
$227 Roundtrip, found 6 days ago
$227
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, May 28 from Knoxville to Des Moines, returning Wed, Jun 4, priced at $227 found 6 days ago
Tue, Jul 1 - Fri, Jul 11
TYS
Knoxville
DSM
Des Moines
$230 Roundtrip, found 6 days ago
$230
Roundtrip
found 6 days ago
Select United flight, departing Tue, Jul 1 from Knoxville to Des Moines, returning Fri, Jul 11, priced at $230 found 6 days ago
Wed, May 28 - Wed, Jun 4
TYS
Knoxville
DSM
Des Moines
$232 Roundtrip, found 6 days ago
$232
Roundtrip
found 6 days ago
Select United flight, departing Wed, May 28 from Knoxville to Des Moines, returning Wed, Jun 4, priced at $232 found 6 days ago
Wed, May 14 - Sun, May 25
TYS
Knoxville
DSM
Des Moines
$237 Roundtrip, found 1 day ago
$237
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, May 14 from Knoxville to Des Moines, returning Sun, May 25, priced at $237 found 1 day ago

More About Flying To Des Moines from Knoxville

Route Information for Flights from Knoxville to Des Moines

Origin Airport IATA Code
TYS
Destination Airport IATA Code
DSM
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Knoxville to Des Moines

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Frequently asked questions

What is the shortest flight from Knoxville to Des Moines?
Keep that binge-watch you had planned for the hotel room, because the trip from Knoxville to Des Moines can take as little as 2 hours and 53 minutes.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.