$138 Cheap flight deals from Des Moines (DSM) to Myrtle Beach (MYR)

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This Weekend's Flight Deals from Des Moines to Myrtle Beach

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, May 3 - Tue, May 20
DSM
Des Moines Intl.
MYR
Myrtle Beach Intl.
$419 Roundtrip, found 2 days ago
$419
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, May 3 from Des Moines Intl. to Myrtle Beach Intl., returning Tue, May 20, priced at $419 found 2 days ago

Airfares from $138 One Way, $276 Round Trip from Des Moines to Myrtle Beach

Prices starting at $276 for return flights and $138 for one-way flights to Myrtle Beach were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 30 - Sun, Aug 31
DSM
Des Moines
MYR
Myrtle Beach
$276 Roundtrip, found 5 days ago
$276
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Aug 30 from Des Moines to Myrtle Beach, returning Sun, Aug 31, priced at $276 found 5 days ago
Sat, Jul 5 - Tue, Jul 15
DSM
Des Moines
MYR
Myrtle Beach
$284 Roundtrip, found 2 days ago
$284
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Jul 5 from Des Moines to Myrtle Beach, returning Tue, Jul 15, priced at $284 found 2 days ago
Tue, Jul 1 - Tue, Jul 15
DSM
Des Moines
MYR
Myrtle Beach
$286 Roundtrip, found 2 days ago
$286
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Jul 1 from Des Moines to Myrtle Beach, returning Tue, Jul 15, priced at $286 found 2 days ago
Mon, Jun 23 - Fri, Jul 4
DSM
Des Moines
MYR
Myrtle Beach
$287 Roundtrip, found 2 days ago
$287
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Jun 23 from Des Moines to Myrtle Beach, returning Fri, Jul 4, priced at $287 found 2 days ago
Tue, May 20 - Sun, May 25
DSM
Des Moines
MYR
Myrtle Beach
$288 Roundtrip, found 2 days ago
$288
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, May 20 from Des Moines to Myrtle Beach, returning Sun, May 25, priced at $288 found 2 days ago

Myrtle Beach economy flight packages

Price found within the past 48 hours. Click for updated prices.
North Shore Oceanfront Resort Hotel with Waterpark
3.5-star property

North Shore Oceanfront Resort Hotel with Waterpark

7.4/10 Good! (1,931 reviews)

Jun 19 - Jun 24

5 night stay

Des Moines (DSM) to Myrtle Beach (MYR)

Delta • Non-stop roundtrip • Coach
per person
found 2 hours ago
Great Experience as Always! Air conditioner in room did not cool room to preferred temperature. Light above table did not work. Toilet clogged and when engineering came they didn’t really say anything. Slightly odd.

Reviewed on Nov 1, 2024

Crown Reef Beach Resort and Waterpark
3.0-star property

Crown Reef Beach Resort and Waterpark

7.6/10 Good! (2,309 reviews)

Jun 19 - Jun 24

5 night stay

Des Moines (DSM) to Myrtle Beach (MYR)

Delta • Non-stop roundtrip • Coach
Save 100% on your flight
per person
found 2 hours ago
My children were able to enjoy themselves without having to leave the resort!!! There was a water park, pools and hot tubs all over the resort!!!! Absolutely fell in love with Ocean Reef!!!

Reviewed on Apr 1, 2025

Palace Resort
2.5-star property

Palace Resort

6.8/10 (743 reviews)

Jun 19 - Jun 24

5 night stay

Des Moines (DSM) to Myrtle Beach (MYR)

Delta • Non-stop roundtrip • Coach
per person
found 2 hours ago
Everyone was nice and polite

Reviewed on Sep 12, 2022

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More About Flying To Myrtle Beach from Des Moines

Route Information for Flights from Des Moines to Myrtle Beach

Origin Airport IATA Code
DSM
Destination Airport IATA Code
MYR
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Des Moines to Myrtle Beach

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Frequently asked questions

What is the shortest flight from Des Moines to Myrtle Beach?
The shortest flight time from Des Moines Intl. Airport (DSM) to Myrtle Beach, SC (MYR-Myrtle Beach Intl.) is 3 hours and 5 minutes. Grab your favorite tipple from the drink trolley, get stuck into your travel journal or get to know your seat mate — you’ll have enough time on this medium-haul journey.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.