$189 Cheap flight deals from Panama City (PTY) to Santo Domingo (SDQ)

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This Weekend's Flight Deals from Panama City to Santo Domingo

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, May 2 - Tue, May 6
PTY
Tocumen Intl.
SDQ
Las Americas Intl.
$336 Roundtrip, found 13 hours ago
$336
Roundtrip
found 13 hours ago
Select avianca flight, departing Fri, May 2 from Tocumen Intl. to Las Americas Intl., returning Tue, May 6, priced at $336 found 13 hours ago

Airfares from $189 One Way, $336 Round Trip from Panama City to Santo Domingo

Prices starting at $336 for return flights and $189 for one-way flights to Santo Domingo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, May 15 - Tue, Jul 1
PTY
Panama City
SDQ
Santo Domingo
$336 Roundtrip, just found
$336
Roundtrip
just found
Select avianca flight, departing Thu, May 15 from Panama City to Santo Domingo, returning Tue, Jul 1, priced at $336 just found
Mon, Jul 7 - Fri, Jul 11
PTY
Panama City
SDQ
Santo Domingo
$340 Roundtrip, found 2 days ago
$340
Roundtrip
found 2 days ago
Select avianca flight, departing Mon, Jul 7 from Panama City to Santo Domingo, returning Fri, Jul 11, priced at $340 found 2 days ago
Sat, Jun 7 - Sat, Jun 21
PTY
Panama City
SDQ
Santo Domingo
$375 Roundtrip, found 4 days ago
$375
Roundtrip
found 4 days ago
Select avianca flight, departing Sat, Jun 7 from Panama City to Santo Domingo, returning Sat, Jun 21, priced at $375 found 4 days ago
Thu, May 15 - Tue, Jul 1
PTY
Panama City
SDQ
Santo Domingo
$412 Roundtrip, just found
$412
Roundtrip
just found
Select avianca flight, departing Thu, May 15 from Panama City to Santo Domingo, returning Tue, Jul 1, priced at $412 just found
Mon, Jul 7 - Fri, Jul 11
PTY
Panama City
SDQ
Santo Domingo
$417 Roundtrip, found 2 days ago
$417
Roundtrip
found 2 days ago
Select avianca flight, departing Mon, Jul 7 from Panama City to Santo Domingo, returning Fri, Jul 11, priced at $417 found 2 days ago

Santo Domingo economy flight packages

Price found within the past 48 hours. Click for updated prices.
Casa Rosada Beach Front
3.0-star property

Casa Rosada Beach Front

9.4/10 Exceptional! (3 reviews)

Jun 19 - Jun 22

3 night stay

Panama City (PTY) to Santo Domingo (SDQ)

Copa • Roundtrip • Coach
per person
found 12 hours ago
Bahia Principe Luxury Bouganville - Adults Only - All Inclusive
4.5-star property

Bahia Principe Luxury Bouganville - Adults Only - All Inclusive

8.8/10 Excellent! (2,588 reviews)

Jun 19 - Jun 22

3 night stay

Panama City (PTY) to Santo Domingo (SDQ)

Copa • Roundtrip • Coach
per person
found 1 day ago
The staff at resort were extremely helpful and friendly. Food was very good. Would have liked drink menus st outdoor bars and indoor bars. Would be helpful when trying to order a drink, . Plenty of places to sit at beach and pool. That was nice. Mini oversized golf carts to take you around resort was great. We would highly recommend this resort.

Reviewed on Apr 13, 2025

Bahia Principe Grand La Romana - All Inclusive
4.5-star property

Bahia Principe Grand La Romana - All Inclusive

8.4/10 Very Good! (2,255 reviews)

Jun 19 - Jun 22

3 night stay

Panama City (PTY) to Santo Domingo (SDQ)

Copa • Roundtrip • Coach
per person
found 1 day ago
THE PEOPLE THERE MAKE THE PROPERTY WHAT IT IS. ONY THING NEGITIVE WAS TRAVEL 1HR FROM AIRPORT.

Reviewed on Apr 8, 2025

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More About Flying To Santo Domingo from Panama City

Route Information for Flights from Panama City to Santo Domingo

Origin Airport IATA Code
PTY
Destination Airport IATA Code
SDQ
Distance
917 mi
Direct Flight Airlines
KLM, Air France, Turkish Airlines, Copa Airlines
Earliest Flight Arrival
3:57PM UTC
Latest Flight Arrival
7:45AM UTC

Panama City to Santo Domingo

If you are looking to find the best deals on Panama City to Santo Domingo flights, look no further than Orbitz. Orbitz offers guaranteed low prices as well as cutting-edge mobile tools to help you book cheap flights from Panama City to Santo Domingo.

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Orbitz keeps you updated on information that’s relevant to your flights from Panama City to Santo Domingo. We can send you and six of your personal contacts free travel alerts via SMS text, voicemail, or email, so you instantly know about flight delays or changes.

Keep More Money in Your Pocket With Discount Flights

Orbitz looks for the best deals on Panama City to Santo Domingo flights for you. Mix and match airlines for your departing and return flights to fit your travel schedule and budget.

Frequently asked questions

Are there non-stop flights from Panama City to Santo Domingo?
Copa Airlines will fly you straight from PTY to Santo Domingo (SDQ-Las Americas Intl.), which means you won’t have to stress about swapping planes or missing your connecting flight on this route.
What is the shortest flight from Panama City to Santo Domingo?
From Panama City, the eclectic sights and sounds of Santo Domingo are at least 4 hours and 15 minutes away. Book your favorite seat, or maybe even one with a bit more legroom, and get to your destination in comfort.
What airlines fly from Panama City to Santo Domingo most frequently?
Copa Airlines is the most frequent airline servicing the Panama City to Santo Domingo route. Choose from 73 flights every month with this carrier.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.