$163 Cheap flight deals from Medellin (MDE) to Panama City (PTY)

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This Weekend's Flight Deals from Medellin to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Airfares from $163 One Way, $284 Round Trip from Medellin to Panama City

Prices starting at $284 for return flights and $163 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
MARINN PLACE Financial District
Central Hotel Panama Casco Viejo
The Gray by Wynwood House
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More About Flying To Panama City from Medellin

Route Information for Flights from Medellin to Panama City

Origin Airport IATA Code
MDE
Destination Airport IATA Code
PTY
Distance
336 mi
Direct Flight Airlines
KLM, Avianca, Copa Airlines, United Airlines
Earliest Flight Arrival
11:34AM UTC
Latest Flight Arrival
12:48AM UTC

Medellin to Panama City

The best fares for Medellin to Panama City flights are always found on Orbitz. With superior discounts and the latest innovations in mobile access, your ideal trip starts with Orbitz.

The Easy Way to Plan Travel Cheaply

We provide access to many low-cost vacation packages and travelers can mix and match airlines when scheduling their flights for the best prices and flight times. Finding cheap tickets on flights from Medellin to Panama City is easy when you make Orbitz your #1 travel planner.

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Our iPhone and Android mobile apps can be used to compare and book flights from Medellin to Panama City. These apps are perfect for checking the status of flights, gate and baggage claims details, car rental rates, and for receiving alerts on special savings that are exclusive to mobile users. Mobile app users can even score great rates when booking hotel rooms. You can compare hotels, virtually view photo galleries, and check out user reviews using the app, as well as find out which ones are closest to you.

Orbitz also offers free travel updates that are sent to your email or mobile phone that notifies you of booking changes, disruptions in service, or delayed flights.

Increase Your Rewards While Enjoying Super Low Rates

Boost your points or miles for your frequent flyer program on certain Medellin to Panama City flights. Simply provide your frequent flyer information when booking flights from Medellin to Panama City with Orbitz and get both a low fare and travel rewards. You can enter this information in your Orbitz account profile for easy remembering in future bookings.

Frequently asked questions

Are there non-stop flights from Medellin to Panama City?
Yes, you can jet from MDE to Panama City (PTY-Tocumen Intl.) with Copa Airlines, the only airline offering nonstop services on this route.
What is the shortest flight from Medellin to Panama City?
Leave that movie marathon for the hotel room, because the flight from Medellin to Panama City can take as little as 1 hour and 9 minutes.
What airlines fly from Medellin to Panama City most frequently?
If you’re looking for the airline that offers the most flights from Medellin to Panama City, Copa Airlines is your best bet. This trusted airline operates 152 flights along this route per month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.