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21c Museum Hotel Louisville

4.5 star property
Luxury hotel with a full-service spa and a 24-hour fitness center

Choose dates to view prices

Photo gallery for 21c Museum Hotel Louisville

Front of property
Interior entrance
Premium bedding, down comforters, minibar, in-room safe
Fountain
Premium bedding, down comforters, minibar, in-room safe

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Spa
  • Room service
  • Pet friendly

Explore the area

Map
700 W Main Street, Louisville, KY, 40202
  • Louisville Slugger Museum
    ‪3 min walk‬
  • Kentucky International Convention Center
    ‪8 min walk‬
  • KFC Yum Center
    ‪8 min walk‬
  • Louisville, KY (SDF-Louisville Intl.)
    ‪10 min drive‬

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Room options

View all photos for Luxury Double Room, 2 Double Beds

Premium bedding, down comforters, minibar, in-room safe

Luxury Double Room, 2 Double Beds

  • 435 sq ft
  • Sleeps 4
  • 2 Double Beds

View all photos for Deluxe Double Room, 2 Double Beds

Premium bedding, down comforters, minibar, in-room safe

Deluxe Double Room, 2 Double Beds

  • 335 sq ft
  • Sleeps 4
  • 2 Double Beds

View all photos for Luxury Room, 1 King Bed

Luxury Room, 1 King Bed | Premium bedding, down comforters, minibar, in-room safe

Luxury Room, 1 King Bed

  • 455 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed | Premium bedding, down comforters, minibar, in-room safe

Deluxe Room, 1 King Bed

  • 350 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Suite, Corner

Suite, Corner | Premium bedding, down comforters, minibar, in-room safe

Suite, Corner

  • Sleeps 3
  • 1 King Bed

Apartment, 1 Double Bed (Rooftop)

  • Sleeps 4
  • 1 Double Bed

Deluxe Double Room, Accessible

  • Sleeps 4
  • 2 Double Beds

Room (Asleep In the Cycl1)

  • Sleeps 3
  • 1 King Bed

Deluxe Room, 1 King Bed, Accessible

  • Sleeps 3
  • 1 King Bed

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Interior detail

Omni Louisville Hotel

Downtown Louisville
  • Pool
  • Spa
  • Pet friendly
  • Free WiFi
9.2 out of 10, Wonderful, 1,406 reviews
The price is $216
includes taxes & fees
$184 per night
May 8 - May 9
Omni Louisville Hotel

About the neighborhood

Louisville

Located in Downtown Louisville, 21c Museum Hotel Louisville is adjacent to Louisville Slugger Museum and within a 10-minute walk of other popular attractions like KFC Yum Center. This 91-room, 4.5-star hotel has a restaurant, a full-service spa, and a 24-hour gym.

What's nearby

  • Louisville Slugger Museum - 3 min walk - 0.2 miles
  • Muhammad Ali Center - 4 min walk - 0.2 miles
  • Kentucky International Convention Center - 8 min walk - 0.5 miles
  • KFC Yum Center - 8 min walk - 0.5 miles
  • Fourth Street Live! - 9 min walk - 0.5 miles

Getting around

  • Louisville Intl. Airport (SDF) - 10 min drive

Restaurants

  • ‪Thelma's Deli - ‬8 min walk
  • ‪Swizzle Dinner & Drinks - ‬8 min walk
  • ‪Evan Williams Bourbon Experience - ‬3 min walk
  • ‪Jockey Silks Bourbon Bar - ‬7 min walk
  • ‪Heine Brothers Coffee - ‬3 min walk

About this property

21c Museum Hotel Louisville

Luxury hotel with a full-service spa and a 24-hour fitness center
Guests staying at 21c Museum Hotel Louisville enjoy access to a full-service spa, a 24-hour gym, and free WiFi in public areas. Valet parking is available for USD 32 per night, and there's also limo/town car service. The front desk has multilingual staff on hand 24/7 to help with concierge services, securing valuables, and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this luxury hotel include meeting rooms, conference space, and a 24-hour business center.
50-inch LCD TVs come with cable channels, and guests can stay connected with free WiFi and wired Internet. Beds are dressed in premium bedding and down comforters, and bathrooms offer hair dryers and designer toiletries. IPod docks, minibars, and espresso makers are also standard. Change of towels is available on request.
Recreational amenities at the hotel include a 24-hour fitness center.

The recreational activities listed below are available either on site or nearby; fees may apply.

Guests can pamper themselves with a trip to the onsite spa, which has 2 treatment rooms. Services include massages.

Awards and affiliations

Eco-Certified Property
This property participates in Green Key Global, a program that measures the property's impact on one or more of the following: environment, community, cultural-heritage, the local economy.
21c Museum Hotel Louisville is listed in the 2014 Condé Nast Traveler Gold List of the world's best places to stay.

Languages

English, German, Spanish

Similar properties

Interior detail

Omni Louisville Hotel

  • Pool
  • Spa
  • Pet friendly
  • Free WiFi
9.2 out of 10, Wonderful, 1,406 reviews
The price is $216
includes taxes & fees
$184 per night
May 8 - May 9
Omni Louisville Hotel

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Electric car charging station on site
  • Limo/town car service
  • Valet parking on site (USD 32 per night; includes in/out privileges)
  • Wheelchair-accessible parking available

Food and drink

  • Daily full breakfast available for a fee: USD 5 to 25 per person
  • A bar/lounge
  • A restaurant
  • Coffee and tea in common areas

Restaurants on site

  • Proof on Main

Things to do

  • 24-hour gym
  • Full-service spa
  • Yoga classes

Family friendly

  • In-room crib
  • Laundry facilities
  • Rollaway/extra bed (surcharge)
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Gift shop/newsstand
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Multilingual staff
  • Porter/bellhop
  • Tour and ticket assistance
  • Turndown service

Business services

  • 24-hour business center
  • 5,000 square feet of conference space
  • Computer station
  • Meeting rooms

Full-service spa

  • 2 treatment rooms
  • In-room massages

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Elevator
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible registration desk

More

  • 1 building
  • 4 floors
  • At least 80% lighting from LEDs
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • Built in 2006
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Blackout drapes
  • Down comforter
  • Free crib
  • Hypo-allergenic bedding
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Bathrobes
  • Designer toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 50-inch LCD TV with premium cable channels
  • iPod dock

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service
  • Minibar

More

  • Air conditioning (climate-controlled)
  • Cleaning products are eco-friendly
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Soundproofed rooms
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4 PM; Check-in end time: midnight
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 40.00 per accommodation, per stay
  • Pet weight must not exceed 50 lbs per pet
  • Food and water bowls are available
  • Service animals exempt from fees

Children and extra beds

  • Rollaway/extra beds are available for USD 30.0 per night
  • Free cribs/infant beds are available

Property payment types

Important information

Fees

  • Service fee: USD 5.00 per accommodation, per stay

These are all of the charges provided to us by the property.

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Fee for full breakfast: approximately USD 5 to 25 per person
  • Valet parking fee: USD 32 per night (in/out privileges)
  • Pet fee: USD 40.00 per accommodation, per stay
  • Service animals are exempt from fees
  • Rollaway bed fee: USD 30.0 per night

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit, and window guards
This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels)
  • Check-in: 4 PM
  • Check-out: 11 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day. Driving? This property offers valet parking (fees apply), along with a car charging station.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A credit card for incidental charges and a government-issued photo ID may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • The credit card used at check-in for incidentals must be in the name of the primary guest who made the reservation.
  • Onsite safety features include a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit, and window guards.
  • This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels).

Additional information about polices, regulations, and more:

  • Reservations need to be made in advance for massage services. Contact the hotel at the phone number listed on your booking confirmation.
  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21c Hotel Louisville
21c Hotel Museum
21c Louisville Hotel
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Louisville 21c Hotel
Louisville 21c Museum
Museum Hotel 21c
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21c Museum Hotel Louisville Hotel Louisville

Frequently asked questions

Is a free cancellation option available at 21c Museum Hotel Louisville?

21c Museum Hotel Louisville provides free cancellation on certain room rates. For more details, review the cancellation policy on our site.

How much does it cost to stay at 21c Museum Hotel Louisville?

As of Apr 25, 2025, prices found for a 1-night stay for 2 adults at 21c Museum Hotel Louisville on May 26, 2025 start from $179.55, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What is there to do near 21c Museum Hotel Louisville?

This hotel is situated in Downtown Louisville, just steps from Louisville Slugger Museum, and within a 10-minute walk of KFC Yum Center and Fourth Street Live!. You'll also find Louisville Waterfront Park and Churchill Downs within a short drive.

Will I be able to park at 21c Museum Hotel Louisville?

Yes, valet parking is offered for USD 32 per night with in/out privileges. Accessible parking and electric car charging are also available for guests.

Is there a spa at 21c Museum Hotel Louisville?

There is a full-service spa available for guests to enjoy and services include massages.

Does 21c Museum Hotel Louisville have a casino at the property?

No, 21c Museum Hotel Louisville doesn't have a casino.

Will I find an indoor pool at 21c Museum Hotel Louisville?

No, there is no indoor pool at this hotel.

What do couples enjoy most about 21c Museum Hotel Louisville?

This boutique hotel offers many amenities for couples, including in-room massages as well as a bar and a restaurant.

Are there hot tubs at 21c Museum Hotel Louisville?

No, there isn't a spa tub at this hotel.

Does 21c Museum Hotel Louisville have a restaurant that serves breakfast?

Yes, 21c Museum Hotel Louisville serves a full breakfast for a surcharge each morning at Proof on Main.

Will 21c Museum Hotel Louisville allow pets to stay free of charge?

Although they can't stay for free, pets are welcome at 21c Museum Hotel Louisville for a fee of USD 40.00 per accommodation, per stay. The property also provides food and water bowls.

Does 21c Museum Hotel Louisville have connecting rooms?

Yes, this hotel has connecting guestrooms you can book for your group event or vacation.

How far is the airport from 21c Museum Hotel Louisville?

The closest major airport to 21c Museum Hotel Louisville is Louisville Intl. Airport (SDF), which is 7.1 mi away (10 minutes by car). Another top airport is Louisville, KY (LOU-Bowman Field), which is located 8.1 mi away (11-minute drive).

Are there rooms with balconies that I can book at 21c Museum Hotel Louisville?

No, you won't find guestrooms with balconies at 21c Museum Hotel Louisville.

21c Museum Hotel Louisville Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 761 out of 1001 reviews
Rating 8 - Good. 138 out of 1001 reviews
Rating 6 - Okay. 57 out of 1001 reviews
Rating 4 - Poor. 25 out of 1001 reviews
Rating 2 - Terrible. 20 out of 1001 reviews

9.6/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.6/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Therese

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

21c is a beautiful hotel!

The 21c is a beautiful hotel and I'm happy I discovered it. The room was very comfortable and the location is in the heart of a nice area of shopping and restaurants. I would highly recommend.
Stayed 1 night in Jan 2025

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Interesting hotel

The last time that we were in Louisville we walked through this museum hotel. It's very unique. The rooms are clean and comfortable. The location is great. We liked the attached bar and restaurant (Proof). One plus with staying here is that you get a nightly "nightcap".
Stayed 2 nights in Jan 2025

10/10 Excellent

Heather

Liked: Cleanliness, staff & service, property conditions & facilities
Only thing we found to be strange or disappointing was the attire of the servers in Proof restaurant. Jeans and sweatshirts really don’t make sense in a high end restaurant
Stayed 3 nights in Jan 2025

10/10 Excellent

Tessa

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staying here was more than a great nights sleep, it was an experience
Stayed 1 night in Jan 2025

10/10 Excellent

John

Traveled with group
Liked: Property conditions & facilities
Beautiful hotel. Very clean and nicely furnished. Loved the open art gallery area. Nice bar for nightcap. Walkable to many tourist attractions.
Stayed 1 night in Jan 2025

10/10 Excellent

Yeon

Liked: Cleanliness, staff & service, property conditions & facilities
Enjoyed the art and friendly staff
Stayed 1 night in Jan 2025

10/10 Excellent

Nithin Kumar Reddy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great stay in downtown

Wonderful stay in a downtown location within walking distance of many museums and situated in a safe area. The rooms were spacious and spotless, and the hotel staff was friendly and accommodating.
Stayed 1 night in Dec 2024

4/10 Poor

Rebecca K

Liked: Cleanliness, property conditions & facilities
Disliked: Staff & service
Stayed 1 night in Dec 2024

10/10 Excellent

Derek

Traveled with partner
Check in was smooth and friendly, the property has an excellent museum on site and a fantastic selection of bourbon at the bar, and the rooms were cozy and clean. We had a great time and will certainly be back!
Stayed 3 nights in Dec 2024

10/10 Excellent

Lynn

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Dec 2024

2/10 Terrible

Yun

Stayed 1 night in Dec 2024

10/10 Excellent

catharine

Traveled with family
Liked: Cleanliness, staff & service, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Jane

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Second stay in the area and chose this place because of the museum and great staff.
Stayed 3 nights in Dec 2024

10/10 Excellent

Masato

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Dec 2024

10/10 Excellent

Andrew

Stayed 1 night in Dec 2024

10/10 Excellent

Samantha

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Dec 2024

10/10 Excellent

BRITTANY

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
There has not been one time I have visited 21c and not been impressed. The staff are so kind, the museum is always amazing, my fave restaurant is like 20 ft away, and the room is always so welcoming and comfortable! Only thing I wish they had was seats in the showers because I could literally sit in there ALL day! Thank you for an amazing, quick staycation!
Stayed 1 night in Dec 2024

10/10 Excellent

Joon, Mount Vernon

Liked: Cleanliness, staff & service, property conditions & facilities
Nice modern facility with quirky museum in side the hotel. Fun little boutique hotel.
Stayed 1 night in Dec 2024

10/10 Excellent

Jeana

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Fun and quirky. Short distance from lots restaurants and venues. The room was quiet, stylish and clean.
Stayed 1 night in Dec 2024

10/10 Excellent

Stefanie

Stayed 1 night in Nov 2024

10/10 Excellent

Erin

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Nov 2024

10/10 Excellent

christin

Traveled with partner, Traveled with family
Liked: Staff & service, amenities, property conditions & facilities
We absolutely love all the art and the creativity in the design of this property. We wanted to explore the downtown area within walking distance of the hotel but the hotel is so nice and comfortable and the artwork all around it was an easy decision to stay inside the hotel. Our room was so comfortable and clean. The only things I would say as a negative experience is not having a source of white noise like a fan blowing and the coffee machine was not quiet, easy or efficient. The beds were so comfortable. The soaps and lotions are awesome. Plenty of seating for us to sit and not be on the bed.
Stayed 1 night in Nov 2024

10/10 Excellent

Steven

Stayed 1 night in Nov 2024

10/10 Excellent

Deron

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really comfortable with nice room service
Stayed 2 nights in Nov 2024

10/10 Excellent

Ethel

Liked: Staff & service, property conditions & facilities, room comfort
Stayed 1 night in Nov 2024

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