Business Hotels in Sikeston, MO
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Featured Sikeston Business Hotels

Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
The price is $98 per night
$98
includes taxes & fees
$85 per night
May 4 - May 5
Pear Tree Inn Sikeston features an indoor pool, an outdoor pool, and a gym. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include free WiFi in public areas, a hot tub, and a business center.
Pool
Hot Tub

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
Free Cancellation
The price is $116 per night
$116
includes taxes & fees
$103 per night
May 4 - May 5
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with luggage storage, dry cleaning/laundry, and securing valuables. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.
Pool
Breakfast included

Drury Inn & Suites Jackson MO
225 Drury Lane, Jackson, MO
Free Cancellation
Reserve now, pay when you stay
The price is $95 per night
$95
includes taxes & fees
$90 per night
May 4 - May 5
Guests of Drury Inn & Suites Jackson MO have access to an indoor pool, a gym, and free WiFi in public areas. There's free parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
The price is $103 per night
$103
includes taxes & fees
$90 per night
May 11 - May 12
Guests of Best Western Plus Sikeston have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a computer station, and express check-out.
Pool
Breakfast included

Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $112 per night
$112
includes taxes & fees
$99 per night
May 6 - May 7
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $81 per night
$81
includes taxes & fees
$72 per night
May 5 - May 6
Guests of Pear Tree Inn Cape Girardeau West enjoy a gym, free WiFi in public areas, and a 24-hour business center. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a TV in a common area.
Breakfast included
Pet friendly

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
The price is $92 per night
$92
includes taxes & fees
$81 per night
May 1 - May 2
Renovated in 2023, Days Inn and Suites by Wyndham Sikeston offers a gym, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a vending machine.
Breakfast included
Pet friendly

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr, Sikeston, MO
The price is $150 per night
$150
includes taxes & fees
$132 per night
May 11 - May 12
Guests staying at Holiday Inn Express & Suites Sikeston Southwest by IHG enjoy an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included

Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd, Jackson, MO
Free Cancellation
Reserve now, pay when you stay
The price is $91 per night
$91
includes taxes & fees
$84 per night
Apr 30 - May 1
At Comfort Suites Jackson-Cape Girardeau, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Breakfast included

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
The price is $114 per night
$114
includes taxes & fees
$99 per night
May 4 - May 5
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included

Quality Inn
2011 North Kingshighway, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $68 per night
$68
includes taxes & fees
$60 per night
May 5 - May 6
Guests of Quality Inn enjoy features like an outdoor pool, free WiFi in public areas, and a computer station. If you decide to drive, there's free parking. The 24-hour front desk has staff always at the ready. Additional amenities include laundry facilities, a TV in a common area, and a vending machine.
Pool
Breakfast included

Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd, Cape Girardeau, MO
Free Cancellation
The price is $94 per night
$94
includes taxes & fees
$78 per night
May 12 - May 13
At Candlewood Suites Cape Girardeau by IHG, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include meeting rooms, a business center, and free newspapers.
Pool
Pet friendly

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $112 per night
$112
includes taxes & fees
$99 per night
May 4 - May 5
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a conference center.
Pool
Hot Tub

Hampton Inn Cape Girardeau I 55 East
207 S Mt Auburn Rd, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $125 per night
$125
includes taxes & fees
$111 per night
May 25 - May 26
At Hampton Inn Cape Girardeau I 55 East, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with luggage storage, dry cleaning/laundry, and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included

Travelodge by Wyndham Dexter
1608 E Business US 60, Dexter, MO
Free Cancellation
Reserve now, pay when you stay
The price is $106 per night
$106
includes taxes & fees
$94 per night
May 8 - May 9
Travelodge by Wyndham Dexter features free WiFi in public areas, a business center, and coffee in a common area. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with luggage storage and tours/tickets. Additional amenities include a meeting room, laundry facilities, and a vending machine.
Pet friendly
Parking included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Sikeston hotels essential information
Accommodation | 261 hotels |
---|---|
Lowest Price | $68 |
Highest Price | $150 |
Popular hotels | Pear Tree Inn Sikeston, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, Drury Inn & Suites Jackson MO, Best Western Plus Sikeston, Drury Inn & Suites Cape Girardeau, Pear Tree Inn Cape Girardeau West, Days Inn and Suites by Wyndham Sikeston, Holiday Inn Express & Suites Sikeston Southwest by IHG, Comfort Suites Jackson-Cape Girardeau, Drury Inn & Suites Sikeston, MO, Quality Inn, Candlewood Suites Cape Girardeau by IHG, Drury Plaza Hotel Cape Girardeau Conference Center, Hampton Inn Cape Girardeau I 55 East, Travelodge by Wyndham Dexter |
Recent Business Hotels Reviews

Pear Tree Inn Sikeston
5/5 Excellent
"Passing through to volunteer with Samaritans Purse we were pleasantly surprised at the loveliness of the hotel. Clean everywhere, great staff, very yummy breakfast buffet. Would highly recommend! "
A verified traveler stayed at Pear Tree Inn Sikeston
Posted 1 day ago
Other Business Hotels
Areas Of Sikeston
Hotels Near
Hotel Themes
Flights To
Top Trending
Hotels
Hotels with Hot Tubs in Cape GirardeauCheap Hotels in ColumbiaHotels in Osage BeachWaterpark Hotels & Resorts in SpringfieldHotels with an Indoor Pool in BransonHotels with Hot Tubs in ColumbiaCheap Hotels in JoplinHotels in SpringfieldKid Friendly Hotels in BransonHotels in Cape GirardeauHotels with Hot Tubs in JoplinWaterpark Hotels & Resorts in BransonHotels in ColumbiaHotels with Hot Tubs in SpringfieldHotels in BransonHotels in St. JosephCheap Hotels in BransonHotels with Hot Tubs in BransonCasino Resorts & Hotels in Branson
Flights
Packages