Quad Cities Vacation Homes

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Featured Vacation Homes in Quad Cities

Don't see what you're looking for?
See all available properties in Quad Cities
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Quad Cities

    Stoney Creek Hotel Quad Cities - Moline

    Stoney Creek Hotel Quad Cities - Moline

    101 18th St, Moline, IL
    The price is $104 per night from Jul 7 to Jul 8
    $104
    per night
    Jul 7 - Jul 8
    8.2/10 Very Good! (1,019 reviews)
    Wyndham Moline on John Deere Commons

    Wyndham Moline on John Deere Commons

    1415 River Dr, Moline, IL
    The price is $84 per night from Jun 9 to Jun 10
    $84
    per night
    Jun 9 - Jun 10
    8.8/10 Excellent! (1,011 reviews)
    Isle Casino Hotel - Bettendorf

    Isle Casino Hotel - Bettendorf

    1777 Isle Pkwy, Bettendorf, IA
    The price is $119 per night from Jun 9 to Jun 10
    $119
    per night
    Jun 9 - Jun 10
    8.2/10 Very Good! (1,001 reviews)

Quad Cities Vacation Homes

Book vacation homes in Quad Cities
Next time you take a group getaway top Quad Cities, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Quad Cities vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Quad Cities vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Quad Cities; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Quad Cities rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Quad Cities is sure to be a winner.

Quad Cities Vacation Homes essential information

Accommodation
92 Vacation Homes
Lowest Price
$84
Highest Price
$125
Popular accommodation
Quiet neighborhood surrounded by parks near multipurpose trail through QC , Lucy’s House Single Family Bungalow, Scenic 1 Bedroom, Enjoy Florida in Illinois; House on Island with Pool, River Front House, The Kruse Cottage, Clean and updated with a Hot Tub Minutes away from the new Bettendorf Waterpark, The river's edge on the Mississippi, Captain's Cove is a county getaway with private ponds for all of life's moments!