Lake City Vacation Homes

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Featured Vacation Homes in Lake City

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Lake City

    La Quinta Inn & Suite by Wyndham Lake City

    La Quinta Inn & Suite by Wyndham Lake City

    165NW CALI DRIVE, Lake City, FL
    The price is $121 per night from Dec 24 to Dec 25
    $121
    includes taxes & fees
    $107 per night
    Dec 24 - Dec 25
    8.8/10 Excellent! (1,011 reviews)
    Americas Best Value Inn Lake City

    Americas Best Value Inn Lake City

    3835 West US Highway 90, Lake City, FL
    The price is $80 per night from Jan 1 to Jan 2
    $80
    includes taxes & fees
    $71 per night
    Jan 1 - Jan 2, 2025
    8.6/10 Excellent! (1,005 reviews)
    Days Inn by Wyndham Lake City I-75

    Days Inn by Wyndham Lake City I-75

    3144 West US Highway 90, Lake City, FL
    The price is $83 per night from Jan 19 to Jan 20
    $83
    includes taxes & fees
    $74 per night
    Jan 19 - Jan 20, 2025
    7.2/10 Good! (1,000 reviews)

Lake City Vacation Homes

Book vacation homes in Lake City
Next time you take a group getaway top Lake City, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Lake City vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Lake City vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Lake City; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Lake City rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Lake City is sure to be a winner.

Lake City Vacation Homes essential information

Accommodation
129 Vacation Homes
Lowest Price
$80
Highest Price
$270
Popular accommodation
Beautiful home 10 minutes from Gilchrist Blue Springs State Park, Quaint rural downtown community close to springs, 3 rivers, biking & equestrian, Float the Ichetucknee for FREE: Tubes/Paddleboards/Kayaks Included- Dogs welcome, Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!, Private 12 acre Ranch sleeps up to 8 on The Santa Fe River., Pet-Friendly Riverfront Lodge on Suwannee River – North Florida Getaway!, Pet-Friendly Florida Escape w/ Patio & Fire Pit!, 6+ Sleeper Farm Escape with HUGE Yard and RV Hookup is Out Standing in its Field, Newberry Home w/ Deck on 10 Acres!