Hotels in Depew

Search over 821 hotels from $81

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Top Rated Depew Hotels

Don't see what you're looking for?
See all available properties in Depew
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What's the best place for a stay in Depew?

What are some favorite hotels in central Depew?

Here are some of our travelers' favorite hotels in downtown Depew:

Not all of the most important sights are in the heart of Depew, so consider a visit to well-known places in the larger area like KeyBank Center.

Depew hotels essential information

Accommodation
821 hotels
Lowest Price
$81
Highest Price
$238
Popular hotels
Garden Place Hotel, Sleep Inn & Suites Buffalo Airport, Buffalo Airport Hotel, Hyatt Regency Buffalo / Hotel and Conference Center, La Quinta Inn & Suites by Wyndham Buffalo Amherst, Wyndham Garden Buffalo Downtown, M Hotel Buffalo, Holiday Inn Express Cheektowaga North East, an IHG Hotel, Hyatt Place Buffalo/Amherst, La Quinta Inn by Wyndham Buffalo Airport, Curtiss Hotel, Ascend Hotel Collection, Best Western Summit Inn

Recent Reviews