Hotels in Southeast Missouri

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Jun 1 - Jun 2
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Top Rated Southeast Missouri Hotels

Auburn Place Hotel And Suites

Auburn Place Hotel And Suites

2.5 out of 5
3265 William St, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
46.97 mi from city center
The price is $79 per night
$79
per night
Jun 2 - Jun 3
Guests staying at Auburn Place Hotel And Suites enjoy an indoor pool, a gym, and free WiFi in public areas. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include a 24-hour business center, a meeting room, and laundry facilities.
Pet friendly
Breakfast included
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
54.5 mi from city center
The price is $70 per night
$70
per night
Jun 9 - Jun 10
Renovated in 2023, Days Inn and Suites by Wyndham Sikeston offers a gym, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a vending machine.
Pet friendly
Breakfast included
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N, Poplar Bluff, MO
Free Cancellation
Reserve now, pay when you stay
29.15 mi from city center
The price is $79 per night
$79
per night
Jun 4 - Jun 5
Guests staying at Motel 6 Poplar Bluff, MO enjoy free WiFi in public areas, laundry facilities, and a vending machine. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with tours/tickets and luggage storage.
Pet friendly
Parking included
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
46.79 mi from city center
The price is $66 per night
$66
per night
Jun 9 - Jun 10
Guests of Pear Tree Inn Cape Girardeau West enjoy a gym, free WiFi in public areas, and a 24-hour business center. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a TV in a common area.
Pet friendly
Breakfast included
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St, Farmington, MO
Free Cancellation
Reserve now, pay when you stay
37.99 mi from city center
The price is $57 per night
$57
per night
Jun 9 - Jun 10
Renovated in 2019, Baymont Inn and Suites by Wyndham Farmington, MO offers a 24-hour gym, free WiFi in public areas, and a conference center. There's free parking and an area shuttle. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and a computer station.
Breakfast included
Pool
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
54.15 mi from city center
The price is $99 per night
$99
per night
Jun 9 - Jun 10
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pet friendly
Breakfast included
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
46.88 mi from city center
The price is $112 per night
$112
per night
Jun 5 - Jun 6
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a spa tub, meeting rooms, and a conference center.
Hot Tub
Pet friendly
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

2.5 out of 5
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
Free Cancellation
Reserve now, pay when you stay
45.7 mi from city center
The price is $91 per night
$91
per night
Jun 3 - Jun 4
Built in 2020, the brand new La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau offers an indoor pool, a 24-hour gym, and free WiFi in public areas. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, laundry facilities, and a vending machine.
Pool
Parking included
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO
46.73 mi from city center
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a spa tub, meeting rooms, and a business center.
Hot Tub
Pet friendly
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

2.5 out of 5
3253 William Street, Cape Girardeau, MO
Free Cancellation
47.02 mi from city center
The price is $117 per night
$117
per night
Jun 9 - Jun 10
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.
Breakfast included
Pool
Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington

2 out of 5
930 Valley Creek Dr, Farmington, MO
Free Cancellation
Reserve now, pay when you stay
39.26 mi from city center
The price is $57 per night
$57
per night
Jun 2 - Jun 3
Super 8 by Wyndham Farmington features free WiFi in public areas, a seasonal outdoor pool, and laundry facilities. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. This smoke-free motel also has a vending machine.
Pet friendly
Breakfast included
Silo Farm Haus- located in the heart of wine country!

Silo Farm Haus- located in the heart of wine country!

41.04 mi from city center
The price is $199 per night
$199
per night
Jun 3 - Jun 4
Guests staying at this farm stay enjoy features like a water park.
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Cheap Southeast Missouri hotels options

    Motel 6 Poplar Bluff, MO

    Motel 6 Poplar Bluff, MO

    4101 Highway 67 N, Poplar Bluff, MO
    The price is $79 per night from Jun 4 to Jun 5
    $79
    per night
    Jun 4 - Jun 5
    8/10 Very Good! (1,001 reviews)
    Auburn Place Hotel And Suites

    Auburn Place Hotel And Suites

    3265 William St, Cape Girardeau, MO
    The price is $79 per night from Jun 2 to Jun 3
    $79
    per night
    Jun 2 - Jun 3
    8.6/10 Excellent! (1,003 reviews)
    Pear Tree Inn Sikeston

    Pear Tree Inn Sikeston

    2602 E Malone Avenue, Sikeston, MO
    The price is $94 per night from Jun 5 to Jun 6
    $94
    per night
    Jun 5 - Jun 6
    9.2/10 Wonderful! (1,000 reviews)
    Super 8 by Wyndham Farmington

    Super 8 by Wyndham Farmington

    930 Valley Creek Dr, Farmington, MO
    The price is $57 per night from Jun 2 to Jun 3
    $57
    per night
    Jun 2 - Jun 3
    8/10 Very Good! (429 reviews)
    Super 8 by Wyndham Pevely

    Super 8 by Wyndham Pevely

    1711 Highway Z, Pevely, MO
    5.6/10 (808 reviews)
    Pear Tree Inn Cape Girardeau West

    Pear Tree Inn Cape Girardeau West

    103 Cape West Pkwy, Cape Girardeau, MO
    The price is $66 per night from Jun 9 to Jun 10
    $66
    per night
    Jun 9 - Jun 10
    8.8/10 Excellent! (1,000 reviews)
Southeast Missouri Hotels

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Great selection of hotels in Southeast Missouri

Whether you're searching for hotels in Southeast Missouri on business, or hunting for a family getaway, Southeast Missouri hotel options are only a click away. Find hotels in Southeast Missouri with the location, star-rating and facilities you need. Narrow your search results even further by star rating, hotel chain and amenities, such as free parking, babysitting services, or fitness centers. And with area maps, you can view Southeast Missouri hotels close you are to the airport and nearby attractions.

Southeast Missouri hotel reviews, photos and virtual tours

Thanks to photos and virtual tours, you can look before you book your Southeast Missouri hotel reservation. Check out Southeast Missouri hotel properties using interactive tools which allow you view hotel rooms, common areas and key features. On Orbitz, you can also learn more about hotels in Southeast Missouri with unbiased reviews from verified Southeast Missouri hotel guests. We ask guests to offer candid feedback on services, comfort, location, value and amenities.

Grab Southeast Missouri hotel deals and special offers

Orbitz works around the clock to find exclusive offers and Southeast Missouri hotel deals, just for you. Sign up for deals by e-mail where you'll get first crack at money-saving extras like promo codes, resort credits, free nights and more. You can also "Like" Orbitz on Facebook and follow us on Twitter to receive up-to-the-minute news on hotel discounts, giveaways and more.

24/7 support with Southeast Missouri hotel reservations

When it comes to finding hotels in Southeast Missouri, an Orbitz specialist can help you find the property right for you. Chat live or call 1-800-454-3743 any time for help booking your hotels in Southeast Missouri. Our team of experts can help you pinpoint Southeast Missouri hotels options suited to your tastes and budget.

Forget Orbitz change or cancel fees on Southeast Missouri hotels

On Orbitz, Southeast Missouri hotel deals mean flexibility. If you need to change your Southeast Missouri hotel reservations, or cancel your stay, Orbitz doesn't charge cancel or change fees. Orbitz also offers great selection on airline tickets, vacation packages, and car rental deals to so you can plan your trip to Southeast Missouri all in one place.

 

Southeast Missouri hotels essential information

Accommodation
570 hotels
Lowest Price
$57
Highest Price
$199
Popular hotels
Auburn Place Hotel And Suites, Days Inn and Suites by Wyndham Sikeston, Motel 6 Poplar Bluff, MO, Pear Tree Inn Cape Girardeau West, Baymont Inn and Suites by Wyndham Farmington, MO, Drury Inn & Suites Sikeston, MO, Drury Plaza Hotel Cape Girardeau Conference Center, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Drury Inn & Suites Cape Girardeau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel, Super 8 by Wyndham Farmington, Silo Farm Haus- located in the heart of wine country!

Recent Reviews

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

5/5 Excellent
"The staff were all friendly and very helpful I brought my mother home to Sikeston for her 92nd Birthday and she got sick in the lobby and the staff helped me with her like she was their own Mom and for that I am forever grateful. I will always stay when you when I return home. Thank You"
A verified traveler stayed at Days Inn and Suites by Wyndham Sikeston
Posted 2 days ago
Days Inn and Suites by Wyndham Sikeston

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